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Sarcoidosis of the external nose: the role of pharmacologic rhinoplasty in diagnosis and treatment

机译:外鼻结节病:药物鼻整形在诊断和治疗中的作用

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摘要

Subcutaneous sarcoidosis is a rare manifestation of a systemic disease. Sarcoidosis most often affects the pulmonary system but can also affect sinonasal tissues including the cutaneous and subcutaneous layers. It can be suspected in patients who may or may not have a prior diagnosis of sarcoidosis but who develop nodules or lesions over the nasal dorsum after trauma or rhinoplasty. The onset may also be spontaneous with diffuse enlargement of the nose. The diagnosis can be confirmed with tissue biopsy. Management is primarily medical with topical, intralesional, or systemic steroids. When medical management has failed, surgical options can be considered. We present a total of four patients with subcutaneous nasal sarcoidosis. Two patients had diffuse subcutaneous sarcoidosis that improved significantly with medical therapy. Two other patients with post-traumatic nodule formation were managed with intralesional steroids and surgery.
机译:皮下结节病是全身性疾病的罕见表现。结节病最常影响肺系统,但也会影响鼻窦组织,包括皮肤和皮下层。可能事先诊断为结节病但在创伤或隆鼻手术后在鼻背上形成结节或病变的患者中可能会怀疑。发作也可能是自发的,鼻子扩散性增大。可以通过组织活检确认诊断。管理主要是使用局部,病灶内或全身性类固醇进行药物治疗。当医疗管理失败时,可以考虑手术选择。我们目前总共有四名皮下鼻结节病患者。两名患者患有弥漫性皮下结节病,经药物治疗可明显改善。其他两名创伤后结节形成的患者接受病灶内类固醇治疗和手术治疗。

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