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首页> 美国卫生研究院文献>EFSA Journal >Safety and efficacy of sodium saccharin when used as a feed flavour for piglets pigs for fattening calves for rearing and calves for fattening
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Safety and efficacy of sodium saccharin when used as a feed flavour for piglets pigs for fattening calves for rearing and calves for fattening

机译：糖精钠用作仔猪育肥猪育肥犊牛和育肥犊牛的饲料香精的安全性和有效性

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Sodium saccharin is intended to be used as a sweetener in feed and water for drinking for piglets, pigs for fattening and veal calves. The Panel on Additives and Products or Substances used in Animal Feed ( ) considers the proposed maximum use level of 150 mg sodium saccharin/kg feed as safe for calves and pigs for fattening. For piglets (sucking and weaned piglets), a lower level of 100 mg sodium saccharin/kg complete feed is considered safe. The corresponding maximum safe concentrations in water for drinking are 30 mg/L for piglets and 50 mg/L for pigs for fattening, respectively. The maximum safe concentrations of sodium saccharin in feed and water for drinking are derived under the premise that only one source, feed or water for drinking, contains the additive. The Panel concludes that no concern for the consumer would result from the use of sodium saccharin in feed and water for drinking at the dose considered safe for the target species. The precautions for handling the product proposed by the applicant are considered to be sufficient to ensure user safety. The Panel concludes that the use of sodium saccharin at the dose considered safe for target species is unlikely to have detrimental effects on the terrestrial and freshwater compartments. The high mobility and relative persistence of saccharin and the high persistency of its degradation product 4‐hydroxysaccharin indicate that groundwater contamination above 0.1 μg/L is likely to occur. Since the function of sodium saccharin in feed for the target species is essentially the same as that in food, the Panel concludes that no demonstration of efficacy is necessary.
机译：糖精钠旨在用作饲料和饮用水中的甜味剂，供仔猪，肥育猪和小牛犊饮用。动物饲料中使用的添加剂和产品或物质小组（）认为建议的150糖精钠/千克饲料的最大使用量对小牛和猪育肥是安全的。对于仔猪（哺乳和断奶仔猪），较低的糖精钠100 mg / kg完全饲料水平被认为是安全的。仔猪饮水的相应最大安全浓度分别为仔猪30 mg / L和育肥猪50 mg / L。在仅一种来源（饲料或饮用水）中含有添加剂的前提下，得出了饲料和饮用水中糖精钠的最大安全浓度。小组得出结论认为，在饲料和饮用水中以目标物种安全的剂量使用糖精钠不会引起消费者的关注。申请人提出的处理产品的预防措施被认为足以确保用户安全。专家小组认为，以糖精钠的剂量认为对目标物种安全的剂量不太可能对陆地和淡水隔室产生有害影响。糖精的高迁移率和相对持久性及其降解产物4-羟基糖精的高持久性表明，可能会发生0.1μg/ L以上的地下水污染。由于目标物种饲料中糖精钠的功能与食品中的糖精基本相同，专家小组认为无需证明其功效是必需的。

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