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首页> 美国卫生研究院文献>Engineering in Life Sciences >Impact of nozzle operation on mass transfer in jet aerated loop reactors. Characterization and comparison to an aerated stirred tank reactor
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Impact of nozzle operation on mass transfer in jet aerated loop reactors. Characterization and comparison to an aerated stirred tank reactor

机译：喷嘴操作对射流充气环流反应器中传质的影响。充气搅拌釜反应器的表征与比较

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摘要

The impact of mass transfer on productivity can become a crucial aspect in the fermentative production of bulk chemicals. For highly aerobic bioprocesses the oxygen transfer rate(OTR) and productivity are coupled. The achievable space time yields can often be correlated to the mass transfer performance of the respective bioreactor. The oxygen mass transfer capability of a jet aerated loop reactor is discussed in terms of the volumetric oxygen mass transfer coefficient k a [h ] and the energetic oxygen transfer efficiency E [kgO  kW  h ]. The jet aerated loop reactor (JLR) is compared to the frequently deployed aerated stirred tank reactor. In jet aerated reactors high local power densities in the mixing zone allow higher mass transfer rates, compared to aerated stirred tank reactors. When both reactors are operated at identical volumetric power input and aeration rates, local k a values up to 1.5 times higher are possible with the JLR. High dispersion efficiencies in the JLR can be maintained even if the nozzle is supplied with pressurized gas. For increased oxygen demands (above 120 mmol L  h ) improved energetic oxygen transfer efficiencies of up to 100 % were found for a JLR compared to an aerated stirred tank reactor operating with Rushton turbines.
机译：传质对生产率的影响可能成为散装化学品发酵生产中的关键方面。对于高氧的生物过程，氧气的传输速率（OTR）和生产力是结合在一起的。可获得的时空产率通常可以与相应生物反应器的传质性能相关。根据体积氧传质系数ka [h]和高能氧传递效率E [kgO kW h]讨论了射流式充气环流反应器的氧传质能力。将射流充气回路反应器（JLR）与经常使用的充气搅拌釜反应器进行了比较。在喷气曝气反应堆中，与曝气搅拌釜反应堆相比，混合区的局部功率密度高，可以实现更高的传质速率。当两个反应堆在相同的体积功率输入和曝气速率下运行时，JLR的局部k a值可能会高出1.5倍。即使向喷嘴提供压缩气体，也可以保持JLR的高分散效率。与使用Rushton涡轮机运行的充气搅拌釜反应器相比，对于JLR，提高的氧气需求量（高于120mmol·L·h）提高了高达100％的高能氧气传输效率。

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