Hemolysis and IgA‐antibodies against tissue transglutaminase: When are antibody test results no longer reliable?

机译：针对组织转谷氨酰胺酶的溶血和IgA抗体：什么时候抗体检测结果不再可靠？

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Antibodies against tissue transglutaminase ( ) of isotype IgA (IgA‐ ) represent reliable diagnostic markers to confirm or exclude celiac disease ( ). Hemolysis ( ) is an important pre‐analytical factor. can be quantified as HL index ( ) correlating with the concentration of free hemoglobin. is abundant in erythrocytes and released upon . In immunoassays, the released may interfere with binding of IgA‐ to the coated TTG.

机译：抗同种型IgA（IgA-）的组织转谷氨酰胺酶（）的抗体是确认或排除乳糜泻（）的可靠诊断标记。溶血（）是重要的分析前因素。可以量化为与游离血红蛋白浓度相关的HL指数（）。富含红细胞并释放。在免疫测定中，释放的物质可能会干扰IgA-与包被的TTG的结合。

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期刊名称 Journal of Clinical Laboratory Analysis
作者
Johannes Wolf; Norman Haendel; Johannes Remmler; Carl Elias Kutzner; Thorsten Kaiser; Thomas Mothes;
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作者单位

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年(卷),期 2018(32),4
年度 2018
页码 -1
总页数 6
原文格式 PDF
正文语种
中图分类生理学;
关键词
autoantibodies; celiac disease; deamidated gliadin; hemolysis index; pre‐analytics;

机译：自身抗体;Celiac疾病;脱醇麦醇溶蛋白;溶血指数;分析前;

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1. Hemolysis and IgA‐antibodies against tissue transglutaminase: When are antibody test results no longer reliable? [J] . Johannes Wolf, Norman Haendel, Johannes Remmler, Journal of clinical laboratory analysis. . 2018,第4期

机译：针对组织转谷氨酰胺酶的溶血和IgA抗体：什么时候抗体检测结果不再可靠？
2. Hemolysis and IgA‐antibodies against tissue transglutaminase: When are antibody test results no longer reliable? [J] . Wolf Johannes, Haendel Norman, Remmler Johannes, Journal of clinical laboratory analysis. . 2018,第4期

机译：针对组织转谷氨酰胺酶的溶血和IgA-抗体：抗体试验结果是什么时候不再可靠？
3. Testing for IgG class antibodies in celiac disease patients with selective IgA deficiency. A comparison of the diagnostic accuracy of 9 IgG anti-tissue transglutaminase, 1 IgG anti-gliadin and 1 IgG anti-deaminated gliadin peptide antibody assays. [J] . Villalta D, Alessio MG, Tampoia M, Clinica chimica acta: International journal of clinical chemistry and applied molecular biology . 2007,第1a2期

机译：在患有选择性IgA缺乏症的腹腔疾病患者中测试IgG类抗体。 9种IgG抗组织转谷氨酰胺酶，1种IgG抗麦醇溶蛋白和1种IgG抗脱氨基醇溶蛋白肽抗体检测方法的诊断准确性的比较。
4. PROFICIENCY TESTING AMONG EUROPEAN LABORATORIES USING AN IMMUNO-FLUORESCENT ANTIBODY TEST (IFAT) FOR THE DETECTION OF ANTIBODIES AGAINST LAWSONIA INTRACELLULARIS IN PIGS [C] . I. Mortimer, H.M.J.F. Van der Heijden, L.E. Henderson, Congress of the International Pig Veterinary Society . 2000

机译：使用免疫荧光抗体试验（IFAT）在猪中的抗体中的欧洲实验室中的能力测试
5. Murine tissue distribution of an antigen recognized by an antibody against the hemochromatosis gene product, HFE, and the role of HFE in intestinal immunology and diabetes. [D] . Meyer, Paul Nicholas. 2002

机译：针对血色素沉着病基因产物HFE的抗体识别的抗原的鼠组织分布，以及HFE在肠道免疫学和糖尿病中的作用。
6. A137 TISSUE-TRANSGLUTAMINASE ANTIBODY HIGHER THAN 10 TIMES THE NORMAL VALUE IS A RELIABLE PREDICTIVE TEST OF VILLOUS ATROPHY IN PATIENTS WITH SUSPICION OF CELIAC DISEASE [O] . T Nguyen, O V Portolese, N Patey, 2019

机译：A137组织转谷氨酰胺酶抗体高于正常值的10倍是怀疑患有宫颈疾病的患者绒毛萎缩的可靠预测试验
7. Hemolysis and IgA-antibodies against tissue transglutaminase: When are antibody test results no longer reliable? [O] . Johannes Wolf, Norman Haendel, Johannes Remmler, 2017

机译：针对组织转谷氨酰胺酶的溶血和IgA-抗体：抗体试验结果是什么时候不再可靠？
8. Using the Method of Fluorescent Antibodies to Investigate the Antigen-Antibody Reaction in Tissues: Studying the Localization of Antinephritic and Antihepatic Antibodies in Homo- and Heterologous Tissues [R] . Kolker, I. I. 1965

机译：使用荧光抗体方法研究组织中的抗原 - 抗体反应：研究同源和异源组织中抗癫痫和抗肝抗体的定位

Hemolysis and IgA‐antibodies against tissue transglutaminase: When are antibody test results no longer reliable?

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