首页> 美国卫生研究院文献>Forensic Science International: Synergy >Screening of new psychoactive substances (NPS) by gas-chromatography/time of flight mass spectrometry (GC/MS-TOF) and application to 63 cases of judicial seizure
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Screening of new psychoactive substances (NPS) by gas-chromatography/time of flight mass spectrometry (GC/MS-TOF) and application to 63 cases of judicial seizure

机译:气相色谱/飞行时间质谱(GC / MS-TOF)筛选新的精神活性物质(NPS)并将其应用于63例司法查封案件中

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摘要

A screening method for the separation and identification of more than fifty NPS is proposed. The method is based on fast gas-chromatography/time of flight mass spectrometry (FAST-GC/MS-TOF). Thanks to the shorter and narrower capillary column and to the rapid acquisition of the TOF detector a huge number of compounds are separated in a very short time of analysis (10 min). Only a few peaks were overlapped. The possibility to apply deconvolution by the software of the GC/MS-TOF instrument allowed the unequivocal identification also for the superimposed peaks. Linearity and LOD was studied and the method was applied to 63 cases of powders seized by the judicial authority at the airport of Milano Malpensa in Northern Italy in the period 2014–2017.
机译:提出了一种分离鉴定五十多种NPS的筛选方法。该方法基于快速气相色谱/飞行时间质谱(FAST-GC / MS-TOF)。由于毛细管柱更短,更窄以及TOF检测器的快速获取,在很短的分析时间内(10分钟)即可分离出大量化合物。只有几个峰重叠。通过GC / MS-TOF仪器的软件进行反卷积的可能性,也可以对叠加的峰进行明确的鉴定。对线性和LOD进行了研究,并将该方法应用于2014-2017年期间意大利司法机构在意大利北部Milano Malpensa机场检获的63例粉末。

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