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首页> 美国卫生研究院文献>Morbidity and Mortality Weekly Report >SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt April 2020
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SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt April 2020

机译：美国海军陆战队成员样本的SARS-CoV-2感染和血清学反应-西奥多·罗斯福号航空母舰2020年4月

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摘要

Compared with the volume of data on coronavirus disease 2019 (COVID-19) outbreaks among older adults, relatively few data are available concerning COVID-19 in younger, healthy persons in the United States ( , ). In late March 2020, the aircraft carrier USS Theodore Roosevelt arrived at port in Guam after numerous U.S. service members onboard developed COVID-19. In April, the U.S. Navy and CDC investigated this outbreak, and the demographic, epidemiologic, and laboratory findings among a convenience sample of 382 service members serving aboard the aircraft carrier are reported in this study. The outbreak was characterized by widespread transmission with relatively mild symptoms and asymptomatic infection among this sample of mostly young, healthy adults with close, congregate exposures. Service members who reported taking preventive measures had a lower infection rate than did those who did not report taking these measures (e.g., wearing a face covering, 55.8% versus 80.8%; avoiding common areas, 53.8% versus 67.5%; and observing social distancing, 54.7% versus 70.0%, respectively). The presence of neutralizing antibodies, which represent antibodies that inhibit SARS-CoV-2, among the majority (59.2%) of those with antibody responses is a promising indicator of at least short-term immunity. This report improves the understanding of COVID-19 in the U.S. military and among young adults in congregate settings and reinforces the importance of preventive measures to lower risk for infection in similar environments.
机译：与成年人中2019年冠状病毒疾病暴发的数据量（COVID-19）相比，美国相对较年轻的健康人群中有关COVID-19的数据相对较少（）。 2020年3月下旬，西奥多·罗斯福号航空母舰抵达关岛港口，此前许多美国机上服务人员研制了COVID-19。 4月，美国海军和疾病预防控制中心对这次暴发进行了调查，该研究报告了在航母上服务的382名服务人员的便利样本中的人口统计，流行病学和实验室检查结果。此次暴发的特征是在该人群中，大部分是年轻健康的成年人，且有密切的，集中的接触，广泛传播，具有相对较轻的症状和无症状感染。报告采取预防措施的服务人员的感染率低于未采取预防措施的服务人员（例如，戴口罩，分别为55.8％和80.8％;避开公共区域，分别为53.8％和67.5％;以及遵守社会疏离政策） ，分别为54.7％和70.0％）。在大多数具有抗体应答的抗体中（59.2％），中和抗体的存在代表抑制SARS-CoV-2的抗体是至少短期免疫的有希望的指标。该报告提高了美国军方和聚集环境中年轻人对COVID-19的理解，并强调了采取预防措施降低在类似环境中感染风险的重要性。

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