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Encapsulation of Bioactive Compounds from Aloe Vera Agrowastes in Electrospun Poly (Ethylene Oxide) Nanofibers

机译:静电纺丝聚环氧乙烷纳米纤维中芦荟类固醇生物活性化合物的包封

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摘要

is an ancient medicinal plant especially known for its beneficial properties for human health, due to its bioactive compounds. In this study, nanofibers with antioxidant activity were successfully obtained by electrospinning technique with the addition of a natural skin extract (AVE) (at 0, 5, 10 and 20 wt% loadings) in poly(ethylene oxide) (PEO) solutions. The successful incorporation of AVE into PEO was evidenced by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (ATR-FTIR), thermogravimetric analysis (TGA) and antioxidant activity by 2,2-diphenyl-1-picrylhydrazyl radical scavenging (DPPH), 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging (ABTS) and ferric reducing power (FRAP) assays. The incorporation of AVE introduced some changes in the PEO/AVE nanofibers morphology showing bimodal diameter distributions for AVE contents in the range 10-20 wt%. Some decrease in thermal stability with AVE addition, in terms of decomposition onset temperature, was also observed and it was more evident at high loading AVE contents (10 and 20 wt%). High encapsulation efficiencies of 92%, 76% and 105% according to DPPH, FRAP and ABTS assays, respectively, were obtained at 5 wt% AVE content, retaining AVE its antioxidant capacity in the PEO/AVE electrospun nanofibers. The results suggested that the obtained nanofibers could be promising materials for their application in active food packaging to decrease oxidation of packaged food during storage.
机译:是一种古老的药用植物,由于其具有生物活性,因此以其对人体健康的有益特性而闻名。在这项研究中,通过静电纺丝技术成功地获得了具有抗氧化活性的纳米纤维,并在聚环氧乙烷(PEO)溶液中添加了天然皮肤提取物(AVE)(0、5、10和20 wt%的负载量)。通过扫描电子显微镜(SEM),傅立叶变换红外光谱(ATR-FTIR),热重分析(TGA)和通过2,2-二苯基-1-吡啶并肼基自由基清除(DPPH)的抗氧化活性证明了AVE成功地掺入了PEO中。 ,2,2'-叠氮基双-(3-乙基苯并噻唑啉-6-磺酸)自由基清除(ABTS)和铁还原能力(FRAP)分析。 AVE的引入使PEO / AVE纳米纤维的形态发生了一些变化,显示AVE含量在10-20 wt%范围内的双峰直径分布。在分解起始温度方面,还观察到随着加入AVE的热稳定性有所降低,并且在高负载AVE含量(10和20wt%)下更明显。在5wt%的AVE含量下,根据DPPH,FRAP和ABTS分析,分别获得了92%,76%和105%的高封装效率,在PEO / AVE电纺纳米纤维中保留了AVE的抗氧化能力。结果表明,所获得的纳米纤维可能是有前景的材料,可用于其在活性食品包装中的应用,以减少包装食品在储存过程中的氧化。

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