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The Influence of Filler Particles on the Mechanical Properties of Maxillofacial Prosthetic Silicone Elastomers: A Systematic Review and Meta-Analysis

机译:填料颗粒对颌面假体硅氧烷弹性体力学性能的影响:系统评价和荟萃分析

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摘要

Although numerous studies have demonstrated the benefits of incorporating filler particles into maxillofacial silicone elastomer (MFPSE), a review of the types, concentrations and effectiveness of the particles themselves was lacking. The purpose of this systematic review and meta-analysis was to review the effect of different types of filler particles on the mechanical properties of MFPSE. The properties in question were (1) tensile strength, (2) tear strength, (3) hardness, and (4) elongation at break. The findings of this study can assist operators, technicians and clinicians in making relevant decisions regarding which type of fillers to incorporate based on their needs. The systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 26 original articles from 1970 to 2019 were selected from the databases, based on predefined eligibility criteria by two reviewers. The meta-analyses of nine papers were carried out by extracting data from the systematic review based on scoring criteria and processed using Cochrane Review Manager 5.3. Overall, there were significant differences favoring filler particles when incorporated into MFPSE. Nano fillers (69.23% of all studies) demonstrated superior comparative outcomes for tensile strength ( < 0.0001), tear strength ( < 0.00001), hardness ( < 0.00001) and elongation at break ( < 0.00001) when compared to micro fillers (30.76% of all studies). Micro fillers demonstrated inconsistent outcomes in mechanical properties, and meta-analysis of elongation at break argued against ( < 0.01) their use. Current findings suggest that 1.5% ZrSiO , 3% SiO , 1.5% Y O , 2–6% TiO , 2–2.5% ZnO, 2–2.5% CeO , 0.5% TiSiO and 1% Ag-Zn Zeolite can be used to reinforce MFPSE, and help the materials better withstand mechanical degradation.
机译:虽然许多研究已经证明将填料颗粒掺入颌面硅氧烷弹性体(MFPSE)中的益处,但缺乏颗粒本身的类型,浓度和有效性的综述。该系统审查和荟萃分析的目的是审查不同类型的填料颗粒对MFPSE机械性能的影响。有问题的性质是(1)拉伸强度,(2)撕裂强度,(3)硬度和(4)伸长率。本研究的调查结果可以帮助运营商,技术人员和临床医生制定有关哪种类型的填充物,以根据其需求纳入哪种类型的填充剂。根据首选报告项目进行系统审查,用于系统评价和荟萃分析(PRISMA)指南。从1970年到2019年的共有26篇原始文章从数据库中选择了两个审稿人的预定资格标准。通过基于评分标准提取来自系统审查的数据和使用Cochrane Review Manager 5.3进行处理,通过从系统审查中提取数据来进行九篇论文的荟萃分析。总体而言,当掺入MFPSE时,有利于填充剂颗粒的显着差异。纳米填料(所有研究的69.23%)显示了与微填料相比(<0.00001),撕裂强度(<0.00001),硬度(<0.00001),硬度(<0.00001),硬度(<0.00001)的伸长率(<0.00001)的伸长率(30.76%)所有研究)。微填料在机械性能方面表现出不一致的结果,并且断裂伸长率的荟萃分析涉及(<0.01)。目前的研究结果表明,1.5%ZRSIO,3%SiO,1.5%yo,2-6%TiO,2-2.5%ZnO,2-2.5%CeO,0.5%Tisio和1%Ag-Zn沸石可用于加强MFPSE ,并帮助材料更好地承受机械降级。

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