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3D Bioprinting in Tissue Engineering for Medical Applications: The Classic and the Hybrid

机译：3D Biemoplint在组织工程中进行医疗应用：经典和杂交

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摘要

Three-dimensional (3D) printing, as one of the most popular recent additive manufacturing processes, has shown strong potential for the fabrication of biostructures in the field of tissue engineering, most notably for bones, orthopedic tissues, and associated organs. Desirable biological, structural, and mechanical properties can be achieved for 3D-printed constructs with a proper selection of biomaterials and compatible bioprinting methods, possibly even while combining additive and conventional manufacturing (AM and CM) procedures. However, challenges remain in the need for improved printing resolution (especially at the nanometer level), speed, and biomaterial compatibilities, and a broader range of suitable 3D-printed materials. This review provides an overview of recent advances in the development of 3D bioprinting techniques, particularly new hybrid 3D bioprinting technologies for combining the strengths of both AM and CM, along with a comprehensive set of material selection principles, promising medical applications, and limitations and future prospects.
机译：三维（3D）印刷作为最常见的近期添加剂制造工艺之一，表明了组织工程领域中的生物结构的强大潜力，最值得注意的是骨骼，整形面包组织和相关器官。 Desirable biological, structural, and mechanical properties can be achieved for 3D-printed constructs with a proper selection of biomaterials and compatible bioprinting methods, possibly even while combining additive and conventional manufacturing (AM and CM) procedures.然而，挑战仍然需要改善印刷分辨率（特别是纳米级），速度和生物材料兼容性以及更广泛的合适的3D印刷材料。本综述概述了最近开发3D生物制品技术的进展，特别是新的混合3D生物印刷技术，用于将AM和CM的优势结合在一起，以及一整套材料选择原理，有希望的医疗应用和局限性和未来前景。

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