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Primary hypothyroidism with exuberant dermatological manifestations

机译:初级甲状腺功能亢进症状旺盛的皮肤病表现

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摘要

Thyroid hormone has effects on the skin. Patients with hypothyroidism have changes such as dry, scaly and rough skin. Increase carotene in the dermis becomes a yellowish tone to the skin of the patient with hypothyroidism. There is an increase in capillary cycle (anagen phase) and nail growth and a reduction in eccrine gland secretion. It is a case of primary hypothyroidism with nail manifestations associated with dermatologic disorders and successful treatment with levothyroxine. Receptors for thyroid hormone have already been found in keratinocytes, fibroblasts, hair follicles and sebaceous glands. Genes responsive to thyroid hormones and elements of the hypothalamic–pituitary–thyroid axis were identified on the skin. This report highlights the importance of cutaneous manifestations as markers of thyroid disease.
机译:甲状腺激素对皮肤产生影响。甲状腺功能减退症的患者具有干燥,鳞状和粗糙的皮肤。增加真皮中的胡萝卜素成为患者皮肤的淡黄色,甲状腺功能亢进。毛细血管循环(Anagen相)和钉子生长增加,并减少了各种各样的腺体分泌。这是一种甲状腺功能减退症的情况,具有与皮肤病病症相关的指甲表现,并用左甲苯胺成功处理。甲状腺激素的受体已经发现在角质形成细胞,成纤维细胞,毛囊和皮脂腺中。在皮肤上鉴定对呼应甲状腺激素和丘脑 - 垂体 - 甲状腺轴的元素的基因被鉴定在皮肤上。本报告突显了皮肤表现为作为甲状腺疾病标记的重要性。

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