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SIZE study: study protocol of a multicentre randomised controlled trial to compare the effectiveness of an interarcuair decompression versus extended decompression in patients with intermittent neurogenic claudication caused by lumbar spinal stenosis

机译：尺寸研究：多期形随机对照试验的研究方案用于比较腰椎脊柱狭窄引起的间歇性神经源性跛行患者的间歇性解压缩与延长减压的延长减压

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摘要

Intermittent neurogenic claudication (INC) is often caused by lumbar spinal stenosis (LSS). Laminectomy is considered a frequently used surgical technique for LSS. Previous studies have shown that laminectomy can potentially cause lumbar instability. Less invasive techniques, preserving midline structures including the bilateral small size interarcuair decompression, are currently applied. Due to lack of evidence and consensus, surgeons have to rely on their training and own experiences to choose the best surgical techniques for their patients. Hence, an observer and patient blinded multicentre, randomised controlled trial was designed to determine the effectiveness and cost-effectiveness of bilateral interarcuair decompression versus laminectomy for LSS.

机译：间歇性神经源性跛行（INC）通常由腰椎狭窄（LSS）引起。椎体切除术被认为是LSS的常用手术技术。以前的研究表明，椎板切除术可能导致腰部不稳定性。目前申请较少的侵入式技术，保存包括双侧小尺寸的中线结构，包括双侧小尺寸的切换减压。由于缺乏证据和共识，外科医生必须依靠他们的培训和自己的经验，为患者选择最佳的手术技巧。因此，观察者和患者致盲的多期体，随机对照试验旨在确定双侧间隔切压对LSS的叠层切除术的有效性和成本效益。

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期刊名称 BMJ Open
作者
Jamie Arjun Sharma; Pravesh S. Gadjradj; Wilco C. Peul; Maurits W. van Tulder; Wouter A. Moojen; Biswadjiet S. Harhangi;
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作者单位

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年(卷),期 2020(10),10
年度 2020
页码 e036818
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
neurosurgery; spine;

机译：神经外科;脊柱;

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1. A Multicenter Prospective Randomized Controlled Clinical Trial to Evaluate the Effectiveness and Safety of a Standalone Percutaneous Interspinous Spacer Versus Decompressive Surgery in Degenerative Lumbar Spinal Stenosis with Neurogenic Intermittent Claud [J] . Meyer Bernhard, LeHuec Jean Charles Journal of neurosurgery. . 2016,第4期

机译：多中心前瞻性随机对照临床试验，以评估退行性腰椎管狭窄合并神经源性间歇性Claud的独立经皮棘突间间隔与减压手术的有效性和安全性
2. Study-protocol for a randomized controlled trial comparing clinical and radiological results after three different posterior decompression techniques for lumbar spinal stenosis: the Spinal Stenosis Trial (SST) (part of the NORDSTEN Study) [J] . Erland Hermansen, Ivar Magne Austevoll, Ulla Kristina Romild, BMC Musculoskeletal Disorders . 2017,第1期

机译：一项用于比较三种不同的后路减压技术治疗腰椎管狭窄症的临床和放射学结果的随机对照试验的研究方案：椎管狭窄试验（SST）（NORDSTEN研究的一部分）
3. X-Stop Resulted in a Higher Reoperation Rate Than Minimally Invasive Decompression, But Both Decreased Symptoms of Neurogenic Intermittent Claudication in Patients with Lumbar Spinal Stenosis [J] . Huddleston Paul The Journal of Bone and Joint Surgery. American Volume . 2015,第22期

机译：X-Stop导致的再手术率高于微创减压术，但两种方法均降低了腰椎管狭窄症患者神经源性间歇性lau行的症状
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6. Study-protocol for a randomized controlled trial comparing clinical and radiological results after three different posterior decompression techniques for lumbar spinal stenosis: the Spinal Stenosis Trial (SST) (part of the NORDSTEN Study) [O] . Erland Hermansen, Ivar Magne Austevoll, Ulla Kristina Romild, 2017

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7. Study-protocol for a randomized controlled trial comparing clinical and radiological results after three different posterior decompression techniques for lumbar spinal stenosis: the Spinal Stenosis Trial (SST) (part of the NORDSTEN Study) [O] . Erland Hermansen, Ivar Magne Austevoll, Ulla Kristina Romild, 2017

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SIZE study: study protocol of a multicentre randomised controlled trial to compare the effectiveness of an interarcuair decompression versus extended decompression in patients with intermittent neurogenic claudication caused by lumbar spinal stenosis

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