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首页> 美国卫生研究院文献>Cancers >Optimization of the Clinical Setting Using Numerical Simulations of the Electromagnetic Field in an Obese Patient Model for Deep Regional Hyperthermia of an 8 MHz Radiofrequency Capacitively Coupled Device in the Pelvis
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Optimization of the Clinical Setting Using Numerical Simulations of the Electromagnetic Field in an Obese Patient Model for Deep Regional Hyperthermia of an 8 MHz Radiofrequency Capacitively Coupled Device in the Pelvis

机译：优化腹部肥胖患者模型中电磁场数值模拟的临床环境优化在骨盆中8MHz射频电容耦合装置的深层区域热疗

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Several randomized controlled trials have shown that the concurrent use of hyperthermia with radiotherapy results in a significant increase in local control rates. However, in studies that analyzed thermal parameters, the radiosensitizing effect required a favorable increase in tumor temperature. A good temperature increase is more difficult to achieve in deep-seated tumors than in superficial tumors. In this study, the reduction of subcutaneous fat overheating, which is a weak point of the deep heating of a capacitively coupled heating system, and the optimization of temperature distribution in the deep regional hyperthermia in the pelvis were investigated using electromagnetic field numerical simulations. In conclusion, the use of overlay boluses, the salt solution concentration in the overlay boluses, and the intergluteal cleft bolus insertion were found to be important for optimizing the temperature distribution. Further studies with numerical simulations based on the patient’s body shape and tumor location are expected.
机译：几种随机对照试验表明，具有放射治疗的热疗同时使用导致局部控制率的显着增加。然而，在分析热参数的研究中，放射敏化效果需要良好地增加肿瘤温度。在深层肿瘤中比在浅表肿瘤中达到良好的温度升高更难以实现。在这项研究中，使用电磁场数值模拟研究了皮下脂肪过热的减少，这是电容耦合加热系统的深度加热的弱点，以及骨盆中深处热疗中的温度分布的优化。总之，发现覆盖钢管中的盐溶液浓度，并发现心悸裂隙插入插入的含盐溶液浓度对于优化温度分布是重要的。预期基于患者体形和肿瘤位置的数值模拟的进一步研究。

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