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Add‐on effect of PSORI‐CM01 to topical calcipotriol for moderate psoriasis vulgaris: A multi‐center randomized double‐blind pilot study

机译：Psori-cm01对局部牛皮癣的局部加链接硫醇的附加效果：多中心随机双盲试验研究

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摘要

Mild‐moderate psoriasis vulgaris is a common dermatological autoimmune condition with limited conventional therapeutic options. Safe and effective adjunct therapies to topical non‐steroidal antipsoriatic therapy are needed. The oral Chinese herbal medicine (CHM) formula PSORI‐CM01 has been evidenced potential antipsoriatic pharmacological activity. This article reports a pilot study which was designed as a double‐blinded, placebo‐controlled randomized controlled trial (RCT) evaluating the effects of PSORI‐CM01 when added to topical calcipotriol cream.

机译：Vill-中度牛皮癣寻常症是一种常见的皮肤病自身免疫病症，常规治疗选择有限。需要安全且有效的辅助疗法，以局部非甾体抗抗抗抗疗法治疗。口腔中草药（CHM）式PSORI-CM01已经证明了潜在的抗抗脂药物活性。本文报告了一个试点研究，该试验研究被设计为双盲，安慰剂对照对照试验（RCT），评价当添加到局部加链接醇霜时Psori-cm01的影响。

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期刊名称 Clinical and Translational Medicine
作者
Shefton Parker; Anthony Lin Zhang; Claire Shuiqing Zhang; Greg Goodman; Zehuai Wen; Yuhong Yan; Danni Yao; Huimei Wu; Hao Deng; Chuanjian Lu; Charlie Changli Xue;
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年(卷),期 2021(11),1
年度 2021
页码 e286
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
calcipotriol; Chinese herbal medicine; clinical trial; pilot; placebo; psoriasis;

机译：Calcipotriol;中草药;临床试验;飞行员;安慰剂;牛皮癣;

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1. 奥沙利铂和卡培他滨联合贝伐单抗加放疗的新辅助方案治疗局部晚期直肠癌:单中心Ⅱ期研究结果 [J] . Xin Yu, De-sen Wan, Pei-rong Ding, 癌症（英文版） . 2018,第008期
2. Add‐on effect of PSORI‐CM01 to topical calcipotriol for moderate psoriasis vulgaris: A multi‐center, randomized, double‐blind pilot study [J] . Shefton Parker, Anthony Lin Zhang, Claire Shuiqing Zhang, Clinical and Translational Medicine . 2021,第1期

机译：Psori-cm01对局部牛皮癣的局部加链接硫醇的附加效果：多中心，随机，双盲试验研究
3. Oral PSORI-CM01, a Chinese herbal formula, plus topical sequential therapy for moderate-to-severe psoriasis vulgaris: pilot study for a double-blind, randomized, placebo-controlled trial [J] . Dan-Ni Yao, Chuan-Jian Lu, Ze-Huai Wen, Trials . 2016,第1期

机译：口服PSORI-CM01，中草药配方，外用序贯疗法治疗中至重度寻常型牛皮癣：一项双盲，随机，安慰剂对照试验的初步研究
4. A phase IIIb, multicentre, randomized, double-blind, vehicle-controlled study of the efficacy and safety of adalimumab with and without calcipotriol/betamethasone topical treatment in patients with moderate to severe psoriasis: the BELIEVE study. [J] . Thaci D, Ortonne JP, Chimenti S, British Journal of Dermatology . 2010,第2期

机译：一项在有或没有卡泊三醇/倍他米松局部治疗中度至重度牛皮癣患者中进行的IIIb期，多中心，随机，双盲，媒介对照的阿达木单抗疗效和安全性研究：BELIEVE研究。
5. MULTI-CENTER, PLACEBO-CONTROLLED, DOUBLE-BLIND, RANDOMIZED STUDY OF ORAL TOCERANIB PHOSPHATE (PALLADIATM, SU11654), A RECEPTOR TYROSINE KINASE INHIBITOR, FOR THE TREATMENT OF DOGS WITH RECURRENT MAS [C] . Cheryl L London, Carolyn J Henry, Anthony W Rusk, Annual conference of the Veterinary Cancer Society . 2008

机译：多中心，安慰剂对照，双盲，随机研究口服Toceranib磷酸盐（Palladia TM，SU11654），受体酪氨酸激酶抑制剂，用于治疗经常性MAS的狗
6. A Double-Blind Randomized Intervention to Reduce Distress from Perceived Cognitive Impairment in Multiple Sclerosis [D] . Glusman, Morgan B. 2019

机译：一种双盲随机干预，以减少多发性硬化症中感知认知障碍的痛苦
7. Oral PSORI-CM01 a Chinese herbal formula plus topical sequential therapy for moderate-to-severe psoriasis vulgaris: pilot study for a double-blind randomized placebo-controlled trial [O] . Dan-Ni Yao, Chuan-Jian Lu, Ze-Huai Wen, 2016

机译：口服PSORI-CM01中草药配方外用序贯疗法治疗寻常型中重度牛皮癣：一项双盲随机安慰剂对照试验的初步研究
8. Oral PSORI-CM01, a Chinese herbal formula, plus topical sequential therapy for moderate-to-severe psoriasis vulgaris: pilot study for a double-blind, randomized, placebo-controlled trial [O] . 2016

机译：口服PSORI-CM01，中草药配方，外用序贯疗法治疗中至重度寻常型牛皮癣：一项双盲，随机，安慰剂对照试验的初步研究

Add‐on effect of PSORI‐CM01 to topical calcipotriol for moderate psoriasis vulgaris: A multi‐center randomized double‐blind pilot study

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