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Three-Dimensional Radiological Assessment of Ablative Margins in Hepatocellular Carcinoma: Pilot Study of Overlay Fused CT/MRI Imaging with Automatic Registration

机译:肝细胞癌中烧蚀的三维放射评估:覆盖融合CT / MRI成像的试验研究

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摘要

Recent advances in fusion imaging technology have made it easier to visualize and estimate ablative margins. This study was conducted to assess the clinical feasibility of a computed tomography (CT)/magnetic resonance imaging (MRI) fusion application for evaluation of the ablative margin in radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). Seventeen patients developed local tumor progressions (LTPs) due to wrong initial evaluations of technical success through a side-by-side comparison, and we reevaluated the ablative margins using the CT/MRI overlay fusion application. Eight patients were categorized into grade C (margin-zero ablation) and nine patients into grade D (existence of residual HCC). LTP occurred in re-graded C patients within 4 to 30.3 months (median, 14.3 months), and in re-graded D patients within 2.4 to 6.7 months (median, 4.2 months) (p = 0.006). Overlay fused CT/MRI imaging can allow us to evaluate HCC ablative margin three-dimensionally with high accuracy.
机译:融合成像技术的最新进展使得可视化和估计消融利润率。进行该研究以评估计算断层摄影(CT)/磁共振成像(MRI)融合应用的临床可行性,用于评估肝细胞癌(HCC)的射频消融(RFA)中的烧蚀余量。 17名患者由于通过并排的比较,由于对技术成功的错误初始评估而产生了本地肿瘤进展(LTPS),并且我们使用CT / MRI覆盖融合申请重新评估了烧蚀的边缘。将8名患者分为C级(边缘零消融)和9名患者进入D级D(残留的HCC存在)。 LTP在4至30.3个月内(中位数,14.3个月)和2.4至6.7个月内的重新评级D患者(中位数,4.2个月)(P = 0.006)中发生。覆盖融合CT / MRI成像可以允许我们三维高精度地评估HCC烧蚀余量。

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