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Bolus Intravenous Procainamide in Patients with Frequent Ventricular Ectopics during Cardiac Magnetic Resonance Scanning: A Way to Ensure High Quality Imaging

机译:推注静脉内普鲁卡因患者在心脏磁共振扫描期间经常心室异位物质:一种保证高质量成像的方法

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摘要

Acquiring high-quality cardiac magnetic resonance (CMR) images in patients with frequent ventricular arrhythmias remains a challenge. We examined the safety and efficacy of procainamide when administered on the scanner table prior to CMR scanning to suppress ventricular ectopy and acquire high-quality images. Fifty consecutive patients (age 53.0 [42.0–58.0]; 52% female, left ventricular ejection fraction 55 ± 9%) were scanned in a 1.5 T scanner using a standard cardiac protocol. Procainamide was administered at intermittent intravenous bolus doses of 50 mg every minute until suppression of the ectopics or a maximum dose of 10 mg/kg. The average dose of procainamide was 567 ± 197 mg. Procainamide successfully suppressed premature ventricular contractions (PVCs) in 82% of patients, resulting in high-quality images. The baseline blood pressure (BP) was mildly reduced (mean change systolic BP −12 ± 9 mmHg; diastolic BP −4 ± 9 mmHg), while the baseline heart rate (HR) remained relatively unchanged (mean HR change −1 ± 6 bpm). None of the patients developed proarrhythmic changes. Bolus intravenous administration of procainamide prior to CMR scanning is a safe and effective alternative approach for suppressing PVCs and acquiring high-quality images in patients with frequent PVCs and normal or only mildly reduced systolic function.
机译:在频繁心律失常心律失常患者中获取高质量的心脏磁共振(CMR)图像仍然是一个挑战。在CMR扫描之前在扫描仪表上施用扫描仪表时,我们检查了普鲁卡酰胺的安全性和有效性,以抑制心室偏见并获得高质量图像。五十次连续患者(53.0岁[42.0-58.0];使用标准心脏协方案,在1.5 T扫描仪中扫描52%的雌性,左心室喷射级分55±9%)。在每分钟的间歇静脉注射剂量剂量为50mg的间歇静脉注射剂量,直至抑制异位物或最大剂量为10mg / kg。 Procainamide的平均剂量为567±197毫克。 Procabainamide在82%的患者中成功地抑制过早的心室收缩(PVC),导致高质量的图像。基线血压(BP)温和地减少(平均变化收缩率BP -12±9 mmHg;舒张压BP -4±9 mmHg),而基线心率(HR)保持相对不变(平均HR改变-1±6 bpm )。没有患者产生过正常变化。在CMR扫描之前,推注静脉内施用Procainamide是一种安全有效的替代方法,用于抑制PVC,并在频繁的PVC患者中获取高质量图像,并且正常或仅轻微降低的收缩功能。

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