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Neurocognitive modeling of latent memory processes reveals reorganization of hippocampal-cortical circuits underlying learning and efficient strategies

机译:潜伏记忆过程的神经认知建模揭示了海马 - 皮质电路的重组基础和高效策略的基础 - 皮质电路

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摘要

a Overall study design. Before training, all children underwent an extensive battery of neuropsychological assessments for intelligence quotient (IQ) and academic achievement. Additionally, before training, each child underwent an fMRI scan session during which they completed Addition (verification of addition equations) and Control (verification of number identities) conditions in a numerical problem-solving task. Upon successful completion of the aforementioned sessions, children went through an intensive 8-week one-to-one training program focused on conceptual aspects of number knowledge and speeded practice on efficient problem-solving strategies and systematic learning of numerical problem solving delivered through 22 lessons of increasing difficulty. Training sessions occurred three times per week and were each 40–50 min in duration. After 8 weeks of training, all children underwent a second fMRI scan session. Adapted from Iuculano et al.14. b Numerical problem-solving skills (assessed by performance on Addition condition) improved significantly with training – performance gains were observed for both accuracy (t(34) = 3.98, p < 0.001, Cohen’s d = 0.75) and reaction time (t(34) = −3.68, p < 0.001, Cohen’s d = −0.70). N = 35 children. Error bar shows standard error of mean. **: p < 0.001. msec: millisecond.
机译:整体研究设计。在培训之前,所有儿童都接受了广泛的智力商(IQ)和学术成就的神经心理学评估电池。另外,在训练之前,每个孩子接受了FMRI扫描会话,在此期间它们完成了添加(附加方程的验证)和控制(验证数字身份的验证)条件在一个数字问题解决任务中。成功完成上述会议后,儿童经历了一个密集的8周一对一的培训计划,专注于数量知识的概念方面,并加速了高效的问题解决策略和系统学习,通过22课程提供了数值问题的系统学习增加难度。培训课程每周发生三次,持续40-50分钟。经过8周的培训后,所有儿童都接受了第二次FMRI扫描会议。改编自Iuculano等。 B数值问题解决技巧(通过添加条件的性能评估)显着改善了训练 - 对于两种精度(T(34)= 3.98,P <0.001,Cohen的D = 0.75)和反应时间(T(34 )= -3.68,p <0.001,Cohen的d = -0.70)。 n = 35个孩子。错误栏显示标准错误的均值。 **:p <0.001。 Msec:毫秒。

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