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Rapid Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Detention Facility Louisiana USA May–June 2020

机译:在2020年5月6月美国拘留设施中严重急性呼吸综合征Coronavirus 2的快速传播

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摘要

To assess transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a detention facility experiencing a coronavirus disease outbreak and evaluate testing strategies, we conducted a prospective cohort investigation in a facility in Louisiana, USA. We conducted SARS-CoV-2 testing for detained persons in 6 quarantined dormitories at various time points. Of 143 persons, 53 were positive at the initial test, and an additional 58 persons were positive at later time points (cumulative incidence 78%). In 1 dormitory, all 45 detained persons initially were negative; 18 days later, 40 (89%) were positive. Among persons who were SARS-CoV-2 positive, 47% (52/111) were asymptomatic at the time of specimen collection; 14 had replication-competent virus isolated. Serial SARS-CoV-2 testing might help interrupt transmission through medical isolation and quarantine. Testing in correctional and detention facilities will be most effective when initiated early in an outbreak, inclusive of all exposed persons, and paired with infection prevention and control.
机译:为了评估经历冠状病毒疾病爆发和评估测试策略的拘留设施中严重急性呼吸综合征冠状病毒2(SARS-COV-2)的传播,我们在美国路易斯安那州的一个设施中进行了一个未来的裁群调查。我们在各个时间点对6个隔离的宿舍中拘留的人进行了SARS-COV-2测试。在143人中,53人在初始测试中呈阳性,另外58人在以后的时间点(累积发病率78%)。在1个宿舍中,所有45名拘留者最初是消极的; 18天后,40名(89%)是阳性的。在SARS-COV-2阳性的人中,47%(52/111)在标本收集时无症状; 14有孤立的复制态病毒。串行SARS-COV-2测试可能通过医学隔离和隔离有助于中断传输。在爆发早期发起时,惩教和拘留设施的测试将是最有效的,包括所有暴露的人,并与感染预防和控制配对。

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