3PC-036 Small-scale compounding using a powder dispensing tool for individualised solid dosage form drug delivery

机译：3pc-036使用粉末分配工具的小规模配混用于个性化固体剂型药物递送

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摘要

Pharmacy compounding is a valuable tool for personalised medicine (e.g. dose and excipients). This is an important tool in drug delivery to children where suitable doses/dosage forms are not available from the pharmaceutical industry. In many cases, liquid-based dosage forms are available allowing for a mL-based, individualised therapy. However, there are cases where capsules are the preferred form. Solid dosage forms allows a child to easily self-administer the medication e.g. during times away from hospital and home such as during school. For many years there have been methods for reformulating tablets by crushing or the use of active pharmaceutical ingredients to fill batches of capsules (e.g. batches of six or 50 or 100 capsules).

机译：药房复合是个性化药物的有价值的工具（例如剂量和赋形剂）。这是药物交付给药物/剂量形式不可用的药物递送的重要工具。在许多情况下，可用于允许基于液体的剂型，允许基于ML的个体化治疗。然而，存在胶囊是优选形式的情况。固体剂型允许儿童轻松自我施用药物。在远离医院和家庭的次数期间。多年来已经通过破碎或使用活性药物成分来填充批次胶囊（例如六或50或100粒）的批次来重新重新重整片剂的方法。

著录项

期刊名称 European Journal of Hospital Pharmacy
作者
O German; M Paulsson;
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作者单位

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年(卷),期 2018(25),Suppl 1
年度 2018
页码 A40
总页数 1
原文格式 PDF
正文语种
中图分类药学;
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1. Solid-solution fibrous dosage forms for immediate delivery of sparingly-soluble drugs: Part 2. 3D-micro-patterned dosage forms [J] . Blaesi Aron H., Saka Nannaji Materials science & engineering . 2021,第Octa期

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2. Transforming lipid-based oral drug delivery systems into solid dosage forms: An overview of solid carriers, physicochemical properties, and biopharmaceutical performance [J] . TanA., RaoS., PrestidgeC.A. Pharmaceutical research . 2013,第12期

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3. Development of clinical dosage forms for a poorly water-soluble drug II: formulation and characterization of a novel solid microemulsion preconcentrate system for oral delivery of a poorly water-soluble drug. [J] . Li P, Hynes SR, Haefele TF, Journal of pharmaceutical sciences. . 2009,第5期

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4. Dissolution testing for prolonged-release solid dosage form containing drug substances degrading in test media.Application to polymeric delivery systems of paracetamol [C] . A A Rakina, T I Spriridonova, S I Tverdokhlebov International Scientific and Technical Youth Conference Perspective Materials of Constructional and Medical Purpose . 2019

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5. In-vitro Evaluations and Physical Characterizations of a Single Solid Dispersion Powder of Diltiazem Hydrochloride for the Development of Multiple Strengths Controlled Release Dosage Forms of the Drug. [D] . Naidu, Srinesh. 2015

机译：盐酸地尔硫卓单一固体分散体粉末的体外评估和物理特性，用于开发药物的多种强度控制释放剂型。
6. Microcrystalline Cellulose Extracted from Native Plants as an Excipient for Solid Dosage Formulations in Drug Delivery [O] . Camila Viera-Herrera, Javier Santamaría-Aguirre, Karla Vizuete, 2020

机译：从天然植物中提取的微晶纤维素作为药物递送中固体剂量配方的赋形剂
7. 3D printed oral solid dosage forms containing hydrochlorothiazide for controlled drug delivery [O] . Gioumouxouzis, Christos I., Katsamenis, Orestis L., Bouropoulos, Nikolaos, 2017

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3PC-036 Small-scale compounding using a powder dispensing tool for individualised solid dosage form drug delivery

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