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Prevalence of Asymptomatic Malaria Infections in Seemingly Healthy Children the Rural Dzanga Sangha Region Central African Republic

机译:看似健康的儿童无症状疟疾感染的患病率中非共和国达冈僧伽地区

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摘要

According to the World Health Organization 94% of global malaria cases and 94% of global malaria deaths have been reported from Africa. Unfortunately, it is difficult to determine the exact prevalence of disease in some African countries due to a large number of asymptomatic cases. The aim of this study was to assess the prevalence of malaria infections in seemingly healthy children living in the Central African Republic (CAR). CareStartTM Malaria HRP2 rapid diagnostic test (RDT) targeting Plasmodium falciparum was used to test a group of 500 asymptomatic children aged 1-15 years old (330 settled Bantu and 170 semi-nomadic BaAka Pygmies) inhabiting the villages in the Dzanga Sangha region (south-west CAR) in March 2020. In total, 32.4% of asymptomatic Bantu and 40.6% of asymptomatic Pygmy children had a positive result of malaria RDT. Our findings allowed us to demonstrate the high prevalence of asymptomatic malaria infections in south-west CAR. RDTs seem to be a useful tool for the detection of Plasmodium falciparum in areas with limited possibilities of using other diagnostic methods, such as light microscopy and molecular biology.
机译:根据世界卫生组织的数据,来自非洲的94%的全球疟疾病例和全球疟疾死亡的94%。不幸的是,由于大量无症状病例,难以确定一些非洲国家的疾病的确切患病率。本研究的目的是评估生活在中非共和国(汽车)的看似健康的儿童中疟疾感染的患病率。 CarestartTM疟疾HRP2快速诊断测试(RDT)靶向疟原虫疟原虫用于测试1-15岁(330岁的班古和170个半游泳型Baaka Pygmies)的500名无症状儿童居住在Dzanga Sangha地区(南方-west汽车)在2020年3月。总共32.4%的无症状肉豆和40.6%的无症状侏儒儿童患有疟疾RDT的积极结果。我们的调查结果让我们展示西南汽车中无症状疟疾感染的高患病率。 RDTS似乎是在使用其他诊断方法的可能性有限的区域中检测疟原虫的有用工具,例如光学诊断和分子生物学。

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