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Lithium in Portuguese Bottled Natural Mineral Waters—Potential for Health Benefits?

机译:葡萄牙语瓶装天然矿泉水 - 健康益处的潜力?

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摘要

There is increasing epidemiologic and experimental evidence that lithium (Li) exhibits significant health benefits, even at concentrations lower than the therapeutic oral doses prescribed as treatment for mental disorders. The aim of this study is to determine the content of Li in 18 brands of bottled natural mineral waters that are available on the Portuguese market and from which the sources are found within the Portuguese territory, to provide data for Li intake from drinking water. Analyses of Li were performed by inductively coupled plasma-mass spectrometry. The results indicate highly different Li concentrations in natural mineral waters: one group with low Li concentrations (up to 11 µg Li/L) and a second group with Li concentrations higher than 100 µg/L. The highest Li concentrations (>1500 µg Li/L) were observed in the highly mineralized Na-HCO3 type waters that are naturally carbonated (>250 mg/L free CO2). As a highly bioavailable source for Li dietary intake these natural mineral waters have potential for Li health benefits but should be consumed in a controlled manner due to its Na and F− contents. The consumption of as little as 0.25 L/day of Vidago natural mineral water (2220 µg Li/L), can contribute up to 50% of the proposed daily requirement of 1 mg Li/day for an adult (70 kg body weight). In future, Li epidemiological studies that concern the potential Li effect or health benefits from Li in drinking water should consider not only the Li intake from tap water but also intake from natural mineral water that is consumed in order to adjust the Li intake of the subjects.
机译:增加了流行病学和实验证据,即锂(Li)表现出显着的健康益处,即使浓度低于作为精神障碍治疗的治疗口服剂量的浓度也是低的。本研究的目的是确定葡萄牙市场上有18个瓶装天然矿泉水中李的含量,并在葡萄牙领土内发现来源,为李摄入量提供饮用水。通过电感耦合等离子体质谱法进行L1的分析。结果表明,天然矿物水中的高度不同的锂浓度:一组低锂浓度(最多11μgLI/ L)和第二组,Li浓度高于100μg/升。在高度矿化的Na-HCO3型水域中观察到最高锂浓度(>1500μg111),其是天然碳酸化的(> 250mg / L FreeCO2)。作为李膳食摄入的高度生物可利用的来源,这些天然矿泉水有潜力益处益处,而且应该由于其Na和F-内容而以受控的方式消耗。消耗只达到0.25升的Vidago天然矿泉水(2220μgLI/ L),可贡献成人(70kg体重)的1 mg Li /天所提出的每日需求的50%。在未来,李流行病学研究涉及潜水的李效应或饮用水中的健康益处应考虑锂摄入自来水,而且还要从消耗的天然矿泉水中摄入,以调整受试者的李摄入量。

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