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首页> 美国卫生研究院文献>The Journal of Clinical and Aesthetic Dermatology >The Role of Skin Care as an Integral Component in the Management of Acne Vulgaris: Part 2: Tolerability and Performance of a Designated Skin Care Regimen Using a Foam Wash and Moisturizer SPF 30 in Patients with Acne Vulgaris Undergoing Active Treatment
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The Role of Skin Care as an Integral Component in the Management of Acne Vulgaris: Part 2: Tolerability and Performance of a Designated Skin Care Regimen Using a Foam Wash and Moisturizer SPF 30 in Patients with Acne Vulgaris Undergoing Active Treatment

机译：皮肤护理在寻常痤疮管理中作为整体组件的作用：第2部分：使用泡沫清洗剂和保湿剂SPF 30的痤疮患者接受主动治疗的指定皮肤护理方案的耐受性和性能

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Proper skin care is considered to be an important component of the total management plan for patients with acne vulgaris. A 28-day, open-label study provided both practical and scientific information on a designated skin care regimen in subjects with acne vulgaris. The cutaneous tolerability overall performance, and assessment of objective parameters evaluating the epidermal permeability barrier were documented with use of a specific foaming skin cleanser and a moisturizer with an SPF 30 broad spectrum rating in actively treated subjects with acne vulgaris. The results were favorable overall with the regimen shown to be nonirritating based on investigator and subject assessments, with high subject satisfaction and cosmetic acceptability ratings reported for both the foaming skin cleanser and the moisturizer with an SPF 30 broad spectrum rating. Objective instrumental testing of transepidermal water loss and epidermal hydration support that this skin care regimen assists in correcting epidermal permeability barrier dysfunctions that are innately present in acne vulgaris, worsened during a flare, and are known to be associated with many medications used to treat acne vulgaris. The recommendation of a specified skin care regimen incorporated into the overall management of acne vulgaris simplifies and standardizes the program for the patient, demonstrates a high level of interest by the clinician, and reduces the risk of the patient self-acquiring facial skin care products that may increase skin irritation.
机译：适当的皮肤护理被认为是寻常痤疮患者总体管理计划的重要组成部分。一项为期28天的开放标签研究为寻常痤疮患者提供了有关指定皮肤护理方案的实用和科学信息。在经过积极治疗的寻常型痤疮患者中，使用特定的起泡皮肤清洁剂和SPF 30广谱等级的保湿剂，记录了皮肤耐受性的总体性能以及评估表皮渗透性屏障的客观参数的评估。结果总体上是令人满意的，根据研究人员和受试者的评估，该方案无刺激性，对于泡沫皮肤清洁剂和保湿剂，均报告了SPF 30广谱等级的高受试者满意度和化妆品可接受性等级。经皮水分流失和表皮水化的客观仪器测试支持这种皮肤护理方案有助于纠正寻常性痤疮中固有的，在发作期间恶化的，已知与许多用于治疗寻常性痤疮的药物有关的表皮渗透性屏障功能障碍。建议将特定的皮肤护理方案纳入寻常性痤疮的整体管理中，从而简化和规范了患者的计划，表明了临床医生的高度关注，并降低了患者自行购买面部皮肤护理产品的风险，可能会增加皮肤刺激性。

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