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首页> 美国卫生研究院文献>The Journal of Clinical and Aesthetic Dermatology >Finger Pad Squamous Cell Carcinoma: Report of Squamous Cell Carcinoma of the Distal Palmar Digit and Review of Associated Risk Factors Mimickers and Treatment of Squamous Cell Carcinoma of Ventral Hand Digits
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Finger Pad Squamous Cell Carcinoma: Report of Squamous Cell Carcinoma of the Distal Palmar Digit and Review of Associated Risk Factors Mimickers and Treatment of Squamous Cell Carcinoma of Ventral Hand Digits

机译：指垫鳞状细胞癌：远端掌指鳞状细胞癌的报道以及相关风险因素Mimickers和腹手部鳞状鳞癌的治疗相关评论

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>BACKGROUND: Squamous cell carcinoma of the palmar digits is rare. >PURPOSE: The authors describe a man with squamous cell carcinoma of the pulp of his left fourth finger, and review the risk factors that may be associated with squamous cell carcinoma development on the ventral digits of the hand. the authors also summarize the clinical differential diagnoses and treatment of squamous cell carcinoma at this location. >METHODS: the authors retrospectively reviewed the literature using PubMed and searched for the following terms: squamous cell carcinoma, squamous cell carcinoma in situ, finger, thumb, palmar, and ventral. Papers were critically evaluated and their cited references reviewed. >RESULTS: Skin biopsy established the patient’s diagnosis. His tumor was excised using Mohs technique with microscopic examination of the tissue margins; viral changes were noted in the keratinocytes. Local or systemic carcinogen exposure, congenital conditions, suppressed host immunity, coincidental bacterial or viral infection, local radiation exposure, and trauma to the affected digit are risk factors associated with the development of palmar digit squamous cell carcinoma. The clinical differential diagnoses of squamous cell carcinoma on the ventral digits include chronic dermatitis and keratoderma, epidermoid cyst, infection, melanoma, and verrucae. Successful treatment involves removal of the tumor; this is usually accomplished by surgical excision of the tumor, which may include some or all of the affected digit. >CONCLUSIONS: The diagnosis of squamous cell carcinoma of the ventral hand digits is often not initially suspected by the patient and/or the clinician. However, despite the occasional delay in diagnosis or subsequent large tumor size, the prognosis for these patients is usually favorable following adequate treatment of the cancer.
机译：>背景：掌指状鳞状细胞癌很少见。 >目的：作者描述了一名男子左四指的牙髓患有鳞状细胞癌，并回顾了与手腹指部鳞状细胞癌发展有关的危险因素。作者还总结了该部位鳞状细胞癌的临床鉴别诊断和治疗。 >方法：作者使用PubMed回顾性研究了文献，并搜索了以下术语：鳞状上皮癌，原位鳞状上皮癌，手指，拇指，手掌和腹侧。对论文进行了严格的评估，并对引用的参考文献进行了审查。 >结果：皮肤活检确定了患者的诊断。使用Mohs技术切除肿瘤，并在显微镜下检查组织边缘。在角质形成细胞中注意到病毒变化。局部或全身致癌物暴露，先天性疾病，宿主免疫力下降，细菌或病毒同时发生感染，局部放射线暴露以及对受影响手指的创伤是与掌指鳞状鳞癌发展相关的危险因素。腹指部鳞状细胞癌的临床鉴别诊断包括慢性皮炎和角化皮，表皮样囊肿，感染，黑色素瘤和疣。成功的治疗包括切除肿瘤。这通常是通过手术切除肿瘤来实现的，其中可能包括部分或全部受影响的手指。 >结论：患者和/或临床医生通常最初并不怀疑诊断腹侧手指鳞状细胞癌。然而，尽管偶尔会延迟诊断或随后出现大的肿瘤，但在适当治疗癌症后，这些患者的预后通常是有利的。

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