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首页> 美国卫生研究院文献>Neurologia medico-chirurgica >Guidelines for Mechanical Thrombectomy in Japan the Fourth Edition March 2020: A Guideline from the Japan Stroke Society the Japan Neurosurgical Society and the Japanese Society for Neuroendovascular Therapy
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Guidelines for Mechanical Thrombectomy in Japan the Fourth Edition March 2020: A Guideline from the Japan Stroke Society the Japan Neurosurgical Society and the Japanese Society for Neuroendovascular Therapy

机译：日本机械血栓切除术指南第四版3月2020年3月：日本中风会日本神经外科学会和日本神经血管治疗学会的指导方针

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Acute cerebral artery occlusion is associated with very poor outcomes.1) Early recanalization of occluded arteries, however, may improve the outcome, and recanalization therapy has been attempted with a variety of approaches. The most well-known approach is intravenous therapy with the recombinant tissue-plasminogen activator (IV rt-PA), alteplase. The efficacy of IV rt-PA has been established through many randomized controlled trials (RCTs).2,3) IV rt-PA is classified as a Class I therapy in the Guidelines for the Early Management of Patients with Acute Ischemic Stroke of the American Heart Association/American Stroke Association (AHA/ASA)4) and a Grade A recommendation in the Japanese Guidelines for the Management of Stroke.5) Even as cerebrovascular medical technology has progressed, IV rt-PA remains the priority therapy for patients with acute ischemic stroke. Currently, IV rt-PA is indicated for acute ischemic stroke within 4.5 hours of onset with no contraindications.6,7)
机译：急性脑动脉闭塞与非常差的结果有关.1）然而，闭塞动脉的早期再生可能改善结果，并尝试了各种方法的重组治疗。最着名的方法是用重组组织 - 纤溶酶原激活剂（IV RT-PA），Alteplase静脉治疗。已经通过许多随机对照试验（RCT）来确定IV RT-PA的疗效.2,3）IV RT-PA被归类为I级治疗，在美国急性缺血性卒中患者的早期管理的准则中心脏协会/美国中风协会（AHA / ASA）4）和日本中风指南的一级建议，即使脑血管医疗技术已经进展，IV RT-PA仍然是急性患者的优先疗法缺血性中风。目前，IV RT-PA在4.5小时内显示出急性缺血性卒中，没有禁忌症.6,7）

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