Validation of soy isoflavone intake and its health effects: a review of the development of exposure biomarkers

机译：大豆异黄酮摄入量及其健康效应验证：对暴露生物标志物的发展综述

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摘要

It is difficult to consistently demonstrate the health effects of soy isoflavones owing to the multitude of factors contributing to their bioavailability. To accurately verify these health effects, dietary isoflavone intake should be measured using a biologically active dose rather than an intake dose. This concept has been expanded to the development of new exposure biomarkers in nutrition research. This review aims to provide an overview of the development of exposure biomarkers and suggest a novel research strategy for identifying the health effects of soy isoflavone intake.

机译：由于促进其生物利用度的众多因素，难以一致地展示大豆异黄酮的健康效果。为了准确验证这些健康效果，应使用生物活性剂量而不是摄入剂量测量膳食异黄酮摄入量。这一概念已经扩大到营养研究中新曝光生物标志物的发展。该审查旨在概述暴露生物标志物的发展，并提出了一种识别大豆异黄酮摄入量的新型研究策略。

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期刊名称 Nutrition Research and Practice
作者
Hwan-Hee Jang; Young-Min Lee; Jeong-Sook Choe; Oran Kwon;
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作者单位

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年(卷),期 2021(15),1
年度 2021
页码 1–11
总页数 11
原文格式 PDF
正文语种
中图分类营养学;
关键词
Soybeans; fermentation; dietary exposure; metabolomics; biological availability; clinical study;

机译：大豆;发酵;膳食暴露;代谢组合;生物学可用性;临床研究;

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专利

1. Early Exposure to Soy Isoflavones and Effects on Reproductive Health: A Review of Human and Animal Studies [J] . Elsa C. Dinsdale, Wendy E. Ward Nutrients . 2010,第11期

机译：大豆异黄酮的早期暴露及其对生殖健康的影响：人类和动物研究综述
2. A Mouse Model for Studying Nutritional Programming: Effects of Early Life Exposure to Soy Isoflavones on Bone and Reproductive Health [J] . Wendy E. Ward, Jovana Kaludjerovic, Elsa C. Dinsdale International Journal of Environmental Research and Public Health . 2016,第5期

机译：研究营养程序的小鼠模型：大豆异黄酮的早期生命暴露对骨骼和生殖健康的影响
3. A Mouse Model for Studying Nutritional Programming: Effects of Early Life Exposure to Soy Isoflavones on Bone and Reproductive Health [J] . Wendy E. Ward, Jovana Kaludjerovic, Elsa C. Dinsdale International Journal of Environmental Research and Public Health . 2016,第5期

机译：研究营养程序的小鼠模型：大豆异黄酮的早期生命暴露对骨骼和生殖健康的影响
4. Interactions between soy isoflavones and other bioactive compounds: a review of their potentially beneficial health effects [C] . Meng-Lei Xu, Jingbo Liu, Chunyi Zhu PSE-PSA meeting . 2015

机译：大豆异黄酮与其他生物活性化合物之间的相互作用：审查其潜在的有益健康影响
5. Development of food frequency questionnaire and database for assessing soy isoflavone intake in the Chinese population. [D] . Chan, Sieu Gaen. 2008

机译：开发食物频率调查表和数据库，以评估中国人口的大豆异黄酮摄入量。
6. Early Exposure to Soy Isoflavones and Effects on Reproductive Health: A Review of Human and Animal Studies [O] . Elsa C. Dinsdale, Wendy E. Ward 2010

机译：大豆异黄酮的早期暴露及其对生殖健康的影响：人类和动物研究综述
7. Early Exposure to Soy Isoflavones and Effects on Reproductive Health: A Review of Human and Animal Studies [O] . Dinsdale, Elsa C., Ward, Wendy E. 2010

机译：大豆异黄酮的早期暴露及其对生殖健康的影响：人类和动物研究综述
8. Research Strategy for Assessing the Health Effects of Exposure to ComplexMixtures. Review of the Office of Research and Development's Draft Strategy for Health Effects Research on Exposure to Complex Mixtures by the Environmental Health Committee [R] . 1991

机译：评估复合混合物暴露对健康影响的研究策略。审查研究和发展办公室关于环境卫生委员会暴露于复杂混合物的健康影响研究战略草案

Validation of soy isoflavone intake and its health effects: a review of the development of exposure biomarkers

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