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Mens sana in corpore sano

机译:一个健全的精神寓于健康的身体

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摘要

Although diet interventions are mostly related to metabolic disorders, nowadays they are used in a wide variety of pathologies. From diabetes and obesity to cardiovascular diseases, to cancer or neurological disorders and stroke, nutritional recommendations are applied to almost all diseases. Among such disorders, metabolic disturbances and brain function and/or diseases have recently been shown to be linked. Indeed, numerous neurological functions are often associated with perturbations of whole-body energy homeostasis. In this regard, specific diets are used in various neurological conditions, such as epilepsy, stroke, or seizure recovery. In addition, Alzheimer’s disease and Autism Spectrum Disorders are also considered to be putatively improved by diet interventions. Glycemic index diets are a novel developed indicator expected to anticipate the changes in blood glucose induced by specific foods and how they can affect various physiological functions. Several results have provided indications of the efficiency of low-glycemic index diets in weight management and insulin sensitivity, but also cognitive function, epilepsy treatment, stroke, and neurodegenerative diseases. Overall, studies involving the glycemic index can provide new insights into the relationship between energy homeostasis regulation and brain function or related disorders. Therefore, in this review, we will summarize the main evidence on glycemic index involvement in brain mechanisms of energy homeostasis regulation.
机译:虽然饮食干预大多数与代谢障碍有关,但如今它们用于各种病理学。从糖尿病和肥胖到心血管疾病,对癌症或神经系统疾病和中风,营养建议应用于几乎所有疾病。在这种紊乱中,最近已被证明是联系的代谢紊乱和脑功能和/或疾病。实际上,许多神经功能通常与全身能量稳定性的扰动相关。在这方面,特定的饮食用于各种神经系统条件,例如癫痫,中风或癫痫发作。此外,Alzheimer的疾病和自闭症谱系障碍也被饮食干预措施被认为能够提高。血糖指数饮食是一种新型开发的指标,预计预期特定食物诱导的血糖变化以及它们如何影响各种生理功能。有几个结果提供了重量管理和胰岛素敏感性低血糖指数饮食效率的效率,也是认知功能,癫痫治疗,中风和神经变性疾病。总体而言,涉及血糖指数的研究可以为能源稳态调控和脑功能或相关疾病之间的关系提供新的见解。因此,在本次审查中,我们将总结关于血糖指数的主要证据参与能源稳态监管的脑机制。

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