首页> 美国卫生研究院文献>Journal of Clinical Medicine >Transthoracic Impedance Measured with Defibrillator Pads—New Interpretations of Signal Change Induced by Ventilations
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Transthoracic Impedance Measured with Defibrillator Pads—New Interpretations of Signal Change Induced by Ventilations

机译:用除颤器电极片测量经胸阻抗—通气引起的信号变化的新解释

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摘要

Compressions during the insufflation phase of ventilations may cause severe pulmonary injury during cardiopulmonary resuscitation (CPR). Transthoracic impedance (TTI) could be used to evaluate how chest compressions are aligned with ventilations if the insufflation phase could be identified in the TTI waveform without chest compression artifacts. Therefore, the aim of this study was to determine whether and how the insufflation phase could be precisely identified during TTI. We synchronously measured TTI and airway pressure (Paw) in 21 consenting anaesthetised patients, TTI through the defibrillator pads and Paw by connecting the monitor-defibrillator’s pressure-line to the endotracheal tube filter. Volume control mode with seventeen different settings were used (5–10 ventilations/setting): Six volumes (150–800 mL) with 12 min−1 frequency, four frequencies (10, 12, 22 and 30 min−1) with 400 mL volume, and seven inspiratory times (0.5–3.5 s) with 400 mL/10 min−1 volume/frequency. Median time differences (quartile range) between timing of expiration onset in the Paw-line (PawEO) and the TTI peak and TTI maximum downslope were measured. TTI peak and PawEO time difference was 579 (432–723) ms for 12 min−1, independent of volume, with a negative relation to frequency, and it increased linearly with inspiratory time (slope 0.47, R2 = 0.72). PawEO and TTI maximum downslope time difference was between −69 and 84 ms for any ventilation setting (time aligned). It was independent (R2 < 0.01) of volume, frequency and inspiratory time, with global median values of −47 (−153–65) ms, −40 (−168–68) ms and 20 (−93–128) ms, for varying volume, frequency and inspiratory time, respectively. The TTI peak is not aligned with the start of exhalation, but the TTI maximum downslope is. This knowledge could help with identifying the ideal ventilation pattern during CPR.
机译:在通气的吹气阶段进行压缩可能会导致心肺复苏(CPR)期间严重的肺损伤。如果可以在TTI波形中确定吹气阶段而没有胸部按压伪影,则经胸阻抗(TTI)可用于评估胸部按压与通气的对齐方式。因此,本研究的目的是确定在TTI期间是否以及如何精确识别吹入阶段。我们通过将监护仪-除颤器的压力线连接到气管内插管过滤器,同步测量了21名同意麻醉的患者的TTI和气道压力(Paw),通过除颤器垫测量了TTI,并且对Paw进行了测量。使用具有17种不同设置的音量控制模式(5-10次通风/设置):六个音量(150-800 mL),具有12 min -1 频率,四个频率(10、12、22和30 min −1 ),体积为400 mL,吸气时间为7次(0.5–3.5 s ),体积为400 mL / 10分钟 -1 频率。测量了爪线(PawEO)呼气开始时间与TTI峰值和TTI最大下坡之间的中位时间差(四分位范围)。 TTI峰值和PawEO时间差为579(432–723) m s 12分钟 -1 < / sup>,与音量无关,与频率呈负相关,并且随吸气时间线性增加(斜率0.47, R 2 = 0.72)。 PawEO和TTI的最大下坡时差在−69和84之间。 m s 用于任何通风设置(时间对齐)。它是独立的( R 2 <0.01)的体积,频率和吸气时间,全局中位数值为−47(−153–65) m < mi mathvariant =“ normal”> s ,− 40(−168–68) m s < / mrow> 和20(−93–128) m s ,用于变化量,频率和吸气时间。 TTI峰与呼气开始不对齐,但TTI最大下坡与呼气开始一致。这些知识可以帮助确定心肺复苏过程中的理想通气模式。

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