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Association between Changes in Nutrient Intake and Changes in Muscle Strength and Physical Performance in the SarcoPhAge Cohort

机译:营养摄入量变化与肌肉力量变化和肌肉力量和岩狼队列的物理性能之间的变化

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摘要

Muscle weakness and physical performance impairment are common geriatric conditions that raise morbidity and mortality. They are known to be affected by nutrition, but only a few longitudinal studies exist. This study aims to fill this gap by exploring the association, over 3 years, between variations of nutrient intakes, as well as, on one side, the variations of handgrip strength, as a surrogate of muscle strength, and on the other side, the physical performance, assessed by gait speed. Participants from the SarcoPhAge study, a Belgian cohort of people aged 65 years and older, were asked to complete a self-administered food frequency questionnaire (FFQ) at the second (T2) and the fifth (T5) year of follow-up. Daily macro- and micronutrient intakes were measured and their changes in consumption over the three years of follow-up were then calculated. The association between changes in nutrients consumption and the variations in muscle parameters were investigated through multiple linear regressions. Out of the 534 participants included in the cohort, 238 had complete data at T2 and T5 (median age of 72.0 years (70.0–78.0 years), 60.9% women). In the cross-sectional analysis, calories, omega-3 fatty acids, potassium, and vitamins D, A, and K intakes were positively correlated with muscle strength. In the longitudinal analysis, neither the gait speed nor the muscle strength changes were significantly impacted by the variations. Other longitudinal investigations with longer follow-up are required to improve knowledge about these interrelations.
机译:肌肉弱点和身体表现障碍是常见的老年病症,提高发病率和死亡率。众所周知,他们被营养影响,但只存在少数纵向研究。本研究旨在通过探索该协会超过3年的营养摄入量的变化,以及一侧,手柄强度的变化,作为肌肉力量的替代品,以及另一方面物理性能,通过步态速度评估。来自讽刺研究的参与者,65岁及以上的比利时人民队列,被要求在第二(T2)和第五(T5)的后续行动中完成自我管理的食物频率调查问卷(FFQ)。每日宏观和微量营养素摄入量被测量,然后计算它们在随访的三年内消费的变化。通过多元线性回归研究了营养消耗量和肌肉参数变化之间的关联。在队列中包含的534名参与者中,238人在T2和T5中完成了完整的数据(72.0岁的中位数(70.0-78.0岁),60.9%的妇女)。在横截面分析中,卡路里,ω-3脂肪酸,钾和维生素D,A和K摄入量与肌肉强度正相关。在纵向分析中,步态速度和肌肉强度变化都没有显着影响变化。需要更长时间的纵向调查,以改善这些相互关系的知识。

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