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Phytoconstituents screening and antimicrobial activity of the invasive species Nicotiana glauca collected from Al-Baha region of Saudi Arabia

机译:从沙特阿拉伯的Al-Baha地区收集的incotive in inicotiana glauca的植物植物培育和抗菌活性

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摘要

Nicotiana glauca belonging to the family Solanaceae is an exotic perinnial bushy species that recently has invaded the mountainous areas of Al-Baha region at the south-west of Saudi Arabia, causing degredation to soil and vegetation composition of those mountains. Accordingly, this plant must be either removed or exploited as a source of useful products such as medicines as it has been proven to contain many effective compounds with therapeutic properties. Thus, the current study aimd to screening N. glauca preliminary phytoconsitiuents and its anticmicrobial activity. Results showed that varying amounts of alkaloids, steroid, tannins, flavonoid, were present in the extracts of N. glauca leaves, stems and flowers. Saponins were present only in the flowers extract. However, all previuos bioactive compounds were absent in the roots except alkaloids, therefore, roots posses lesser amount of the phytoconstituents compared to the other parts of the plants. Leaves extracts inhibited the growth of E. coli (16.3 ± 0.71 mm) and also inhibited the growth of S. aureus (11.0 ± 0.23 mm), while, the flower extracts also inhibited the growth of E. coli (6.7 ± 0.65 mm), and also inhibited the growth of S. aureus (15.8 ± 0.52 mm). This result coincide with the previous results of the screening of N, glauca phytochemicals where the highest amounts found in leaves and flowers extracts. The inhibition zone of the antibiotic gentamycin (reference control) were 32 mm in S. aureus and 38 mm in E. coli. The inhibition zone of gentamycin (reference control) were 32 mm in S. aureus and 38 mm in E. coli. The minimum inhibitory concentration (MIC) of ethyl acetate was ranged (1.5–2 mg/ml). The lower MIC is an indication of high effectiveness of extract. Therefore, such bioactive property would support the idea that removing N. glauca from the mountainous areas of Al-Baha, Saudi Arabia, is not the only solution, but the plant can be exploited as a beneficial source of medicinal and economic purposes such as; antibacterial, antifungal and insecticidal, however, further comprehensive exploration is recommended to confirm such propreties.
机译:尼科尼亚·葡糖属于家庭Solanaceae是一种异国情调的受限浓密物种,最近曾在沙特阿拉伯西南部的Al-Baha地区的山区侵略,导致这些山脉的土壤和植被组成。因此,必须将该植物移除或被利用,作为有用的产品,例如药物,因为它已被证明含有许多具有治疗性质的有效化合物。因此,目前的研究旨在筛选N.Glauca初步植物植物及其反对植物活性。结果表明,在N.Glauca叶,茎和花的提取物中存在不同量的生物碱,类固醇,类宁,黄酮类化合物。皂苷只存在于花提取物中。然而,除了生物碱之外的根部中不存在所有PREGIOS生物活性化合物,因此,与植物的其他部分相比,根部具有较少量的植物植物。叶片提取物抑制大肠杆菌(16.3±0.71mm)的生长,并且还抑制了金黄色葡萄球菌(11.0±0.23mm)的生长,而花提取物也抑制了大肠杆菌的生长(6.7±0.65 mm) ,并且还抑制了金黄色葡萄球菌的生长(15.8±0.52毫米)。该结果与筛选的筛选结果一致,其中叶片和花提取物中发现的最高量。抗生素庆大霉素(参考对照)的抑制区在S.UUREUS和大肠杆菌中的38mM中为32mm。庆大霉素(参考对照)的抑制区在S.UUREUS中为32mm,在大肠杆菌中38mm。乙酸乙酯的最小抑制浓度(MIC)范围(1.5-2mg / ml)。较低的MIC表明提取物的高效性。因此,这种生物活性物业将支持从沙特阿拉伯山区山区去除N.Glauca的想法,这不是唯一的解决方案,但该植物可以被利用为药用和经济目的的有益来源;然而,建议抗菌,抗真菌和杀虫剂进一步综合勘探来确认这些表现。

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