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RDNA-14. RADIATION-INDUCED miR-4516 CONTRIBUTES TO RADIO-RESISTANCE AND PROMOTES AGGRESSIVE PHENOTYPE IN GLIOBLASTOMA

机译：RDNA-14。辐射诱导的miR-4516有助于耐抗抗抗抗抗抗抗胶质母细胞瘤

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Glioblastoma is the most aggressive brain tumor with poor prognosis despite the best available treatment. MicroRNAs (miRNAs) are emerging as promising, novel prognostic biomarkers and therapeutic targets in glioblastoma. In a previous study, we demonstrated that miR-4516 predicts poor prognosis and functions as an oncogene in glioblastoma. Aim of the current study is to examine the role miR-4516 in radiation resistance and identify downstream targets contributing to this phenotype

机译：尽管最佳的可用治疗，胶质母细胞瘤是最具侵略性的脑肿瘤，但预后差。 MicroRNAS（MIRNA）正在涌现为有前途的新推出的胶质母细胞瘤的预后生物标志物和治疗靶标。在以前的一项研究中，我们证明MIR-4516预测预后差和用作胶质母细胞瘤的癌基因。目前的研究目的是检查辐射抗性中的角色-4516，识别促进该表型的下游靶标

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期刊名称 Neuro-Oncology
作者
Ebin Sebastian; Tiantian Cui; Erica Hlavin Bell; Joseph McElroy; Benjamin Johnson; Pooja Manchanda Gulati; Marjolein Geurts; Aline Paixao Becker; Jessica Fleming; S Jaharul Haque; Pierre Robe; Arnab Chakravarti;
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年(卷),期 2019(21),Suppl 6
年度 2019
页码 vi209–vi210
总页数 2
原文格式 PDF
正文语种
中图分类神经病学;肿瘤学;
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专利

1. S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma [J] . Dipak Sapkota, Ove Bruland, Himalaya Parajuli, BMC Cancer . 2015,第1期

机译：S100A16促进口腔鳞状细胞癌的分化并导致侵袭性较小的肿瘤表型
2. S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma [J] . Dipak Sapkota, Ove Bruland, Himalaya Parajuli, BMC Cancer . 2015,第1期

机译：S100A16促进口腔鳞状细胞癌的分化并导致侵袭性较小的肿瘤表型
3. Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer [J] . SunagaN., ImaiH., ShimizuK., International Journal of Cancer =: Journal International du Cancer . 2012,第8期

机译：致癌性KRAS诱导的白细胞介素8过度表达促进细胞生长和迁移，并促进非小细胞肺癌的侵袭性表型
4. Pre-operative Overall Survival Time Prediction for Glioblastoma Patients Using Deep Learning on Both Imaging Phenotype and Genotype [C] . Zhenyu Tang, Yuyun Xu, Zhicheng Jiao, International Conference on Medical Image Computing and Computer-Assisted Intervention . 2019

机译：胶质母细胞瘤患者术前总生存时间的预测在成像表型和基因型上的深度学习
5. Characterizing Glioblastoma Multiforme by Linking Molecular Profiles to Macro Phenotypes [D] . Lewis, Erika. 2021

机译：通过将分子曲线连接到宏观表型来表征胶质母细胞瘤多形状
6. Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer [O] . Noriaki Sunaga, Hisao Imai, Kimihiro Shimizu, -1

机译：致癌kras诱导的白细胞介素-8过表达促进细胞生长和迁移有助于非小细胞肺癌的侵袭性表型
7. S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma [O] . 2015

机译：S100A16促进口腔鳞状细胞癌的分化并促进其侵袭性较小的肿瘤表型

RDNA-14. RADIATION-INDUCED miR-4516 CONTRIBUTES TO RADIO-RESISTANCE AND PROMOTES AGGRESSIVE PHENOTYPE IN GLIOBLASTOMA

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