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Enterovirus-related rhombencephalitis and myelitis in the third trimester of pregnancy: A case report highlighting clinico-radiological findings at diagnosis and follow-up

机译:肠道病毒相关的牙髓炎和怀孕三个三个月的骨髓炎:案例报告突出诊断和随访临床放射性调查结果

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摘要

Rhombencephalitis (RE) refers to inflammatory diseases involving the brainstem and cerebellum. Although RE is a rare entity, it is associated with high morbidity and mortality. The management of such patients is often challenging in terms of identifying the etiology and defining prognosis. Infections, autoimmune and paraneoplastic conditions are commonly implicated. Patients with RE often present with a biphasic illness with an initial flu-like syndrome followed by brainstem dysfunction. CSF pleocytosis, abnormal brain MRI findings, isolation of organism or molecular (PCR/antigen) detection in CSF/blood cultures/stool samples and nasal/rectal swabs help in arriving at a definitive or probable diagnosis. Prompt aggressive treatment with antibacterial and antiviral drugs and/or immunoglobulins along with supportive therapy is crucial for avoiding a poor outcome.
机译:rhombencephalitis(RE)是指患有脑干和小脑的炎症性疾病。虽然RE是一种罕见的实体,但它与高发病率和死亡率有关。这些患者的管理往往在识别病因和定义预后而挑战。通常涉及感染,自身免疫和榫胞骨塑料条件。 RE的患者经常用双相疾病呈现,具有初始流感综合征,然后进行脑干功能障碍。 CSF型血小痘,异常脑MRI调查结果,生物体的分离或分子(PCR /抗原)检测CSF /血液培养/粪便样品和鼻腔/直肠拭子有助于到达最终或可能的诊断。用抗菌和抗病毒药物和/或免疫球蛋白的迅速治疗以及支持性治疗对于避免较差的结果至关重要。

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