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首页> 美国卫生研究院文献>SAGE Open Medical Case Reports >Survival of an infant with massive fetomaternal hemorrhage with a neonatal hemoglobin concentration of 1.2 g/dL without evident neurodevelopmental sequelae
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Survival of an infant with massive fetomaternal hemorrhage with a neonatal hemoglobin concentration of 1.2 g/dL without evident neurodevelopmental sequelae

机译：具有巨大胎儿出血的婴儿的生存新生儿血红蛋白浓度为1.2g / dl没有明显神经发育后遗症

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摘要

Fetomaternal hemorrhage is referred to as the passage of fetal blood into the maternal circulation. Massive hemorrhage can cause severe fetal anemia, affecting fetal and neonatal outcomes. A neonatal hemoglobin concentration (Hb), which is reportedly a significant prognostic factor, of <5.0 g/dL has been reported to carry a high risk of poor outcomes (death and major morbidity). We present a case of massive fetomaternal hemorrhage with the lowest value of neonatal Hb ever previously reported in a survivor, who subsequently met all the developmental milestones at the corrected age of 18 months. A male infant born at 27 weeks gestation, weighing 998 g, presented with severe anemia with an Hb of 1.2 g/dL and an HbF level in the mother’s blood of 2.4%, which led to a diagnosis of fetomaternal hemorrhage. Since there were no findings of hypovolemia, exchange transfusion was performed for prompt correction of the severe anemia without precipitating volume overload. The present case suggested that exchange transfusion might promptly correct anemia in patients with fetomaternal hemorrhage without hypovolemia without causing volume overload.
机译：胎母出血被称为的胎儿血通入母体循环。大量出血可导致严重的胎儿贫血，影响胎儿和新生儿的结果。新生儿血红蛋白浓度（HB），这是一个据说预后显著因素，5.0克/升已上报<携带不良后果（死亡和严重并发症）的高风险。我们目前与以前曾经在一个幸存者报道新生儿血红蛋白的最低值，谁随后在18个月的矫正年龄符合所有发展的里程碑大量胎母输血的情况。一个男婴出生在27孕周，体重998克，提出用1.2克/分升的血红蛋白，并在母亲的血液的2.4％，这导致胎母输血的诊断的HbF的水平严重贫血。由于没有低血容量的研究结果，是为严重贫血的迅速纠正无沉淀体积超负荷进行交换输血。本案建议换血的可能，及时纠正贫血患者胎母输血无血容量减少，而不会造成容量负荷过重。

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