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首页> 美国卫生研究院文献>Therapeutic Advances in Infectious Disease >Antimicrobial stewardship programs; a two-part narrative review ofstep-wise design and issues of controversy. Part II: Ten questions reflectingknowledge gaps and issues of controversy in the field of antimicrobialstewardship
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Antimicrobial stewardship programs; a two-part narrative review ofstep-wise design and issues of controversy. Part II: Ten questions reflectingknowledge gaps and issues of controversy in the field of antimicrobialstewardship

机译：抗微生物管道计划;两部分叙述审查逐步设计和争议问题。第二部分：反映十个问题知识差距和抗菌药物领域的争议问题管家

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Regardless of one’s opinion on antimicrobial stewardship programs (ASPs), it ishardly possible to work in hospital care and not be exposed to the term or itspractical effects. Despite the term being relatively new, the number ofpublications in the field is vast, including several excellent reviews ofgeneral and specific aspects. Work in antimicrobial stewardship is complex, andinclude aspects not only of infectious disease and microbiology, but also ofepidemiology, genetics, behavioural psychology, systems science, economics andethics, to name but a few. This review aims to take several of these aspects andthe scientific evidence from antimicrobial stewardship studies and merge theminto two questions: How should we design ASPs based on what we know today? andWhich are the most essential unanswered questions regarding antimicrobialstewardship on a broader scale? This narrative review is written in two separateparts aiming to provide answers to the two questions. The first part, publishedseparately, is written as a step-wise approach to designing a stewardshipintervention based on the pillars of unmet need, feasibility, scientificevidence and necessary core elements. It is written mainly as a guide to someonenew to the field. It is sorted into five distinct steps; (a) focusing ondesigning aims; (b) assessing performance and local barriers to rationalantimicrobial use; (c) deciding on intervention technique; (d) practical,tailored design including core element inclusion; and (e) evaluation andsustainability. This second part formulates 10 critical questions oncontroversies in the field of antimicrobial stewardship. It is aimed atclinicians and researchers with stewardship experience and strives to promotediscussion, not to provide answers.
机译：无论对抗微生物管理计划（ASP）的意见如何，它是几乎不能在医院照顾中工作，而不是暴露于术语或其实际效果。尽管术语相对较新，但数量该领域的出版物是巨大的，包括几个优秀的评论一般和具体方面。在抗微生物管道工作是复杂的，而且不仅包括传染病和微生物学的方面，还包括流行病学，遗传学，行为心理学，系统科学，经济学和道德，名字，但几个。此评论旨在采取其中几个方面和来自抗微生物管制研究并合并它们的科学证据分为两个问题：我们如何根据我们今天所知的基础设计ASP？和这是有关抗微生物的最重要的未答复问题更广泛的管道上的管道？这个叙述审查是用两个单独的旨在为两个问题提供答案。第一部分，发表另外，被编写为设计管理的一系列态度基于未满足需要的支柱，可行性，科学的支柱的干预证据和必要的核心要素。它主要是作为某人的指导这个领域的新手。它分为五个不同的步骤; （a）专注于设计目标; （b）评估理性的表现和地方障碍抗菌用途; （c）决定干预技术; （d）实用，量身定制的设计包括核心元素包容性;和（e）评估和可持续性。第二部分制定了10个关键问题抗菌管理领域的争论。它的目标是临床医生和研究人员，带着管家经验，努力推广讨论，不提供答案。

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