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首页> 美国卫生研究院文献>Journal of Hip Preservation Surgery >Autologous matrix-induced chondrogenesis and bone marrow aspirate concentrate compared with microfracture for arthroscopic treatment of femoroacetabular impingement and chondral lesions of the hip: bridging the osteoarthritis gap and facilitating enhanced recovery
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Autologous matrix-induced chondrogenesis and bone marrow aspirate concentrate compared with microfracture for arthroscopic treatment of femoroacetabular impingement and chondral lesions of the hip: bridging the osteoarthritis gap and facilitating enhanced recovery

机译：基质基质诱导的软骨发生和骨髓吸气浓缩物与微裂缝进行微裂缝用于关节镜检查股骨诊断和髋关节骨的骨性病变：桥接骨关节炎间隙并促进增强的恢复

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In an attempt to bridge the osteoarthritis (OA) gap, this study compared biological reconstruction with traditional microfracture (MF) techniques in patients with femoroacetabular impingement and focal cartilage defects. Cohorts of two groups were investigated; age, gender and Tonnis grade matched comparison for outcomes between MF and newer biological reconstruction techniques hip arthroscopy surgery using autologous matrix-induced chondrogenesis and bone marrow aspirate combination. Outcomes investigated were pre-op and post-op mean iHOT-12 scores up to 18 months after surgery with a Kaplan–Meier survivorship analysis. Of 111 patients, 46 patients underwent MF and 65 biological reconstruction hip arthroscopy including cam/pincer osteoplasty and labral repair surgery. Age range was 20–69, mean age 45 years for both groups, Tonnis grading was as follows: Grade 0: 26% versus 30%, Grade 1: 52% versus 47% and Grade 2: 22% versus 23% in MF and biological reconstruction groups, respectively. The mean post-operative iHOT-12 score differences between MF and biological reconstruction were significant at 1-year minimum follow-up (P = 0.01, SD 2.8). Biological reconstruction allowed for an enhanced recovery protocol. The MF group had a 67.4% survivorship for conversion to hip replacement at 18 months (32.6% failure rate for any reason) and biological reconstruction had 100% survivorship at 18 months post-operatively with no failures for any reason. This study provides further support to the evidence base for biological reconstructive techniques as superior to MF in combination with joint preservation arthroscopic surgery, even in the face of focal cartilage defects and offers both surgeons and patients a potential bridging of the OA gap.
机译：在试图桥接骨关节炎（OA）的间隙，该研究比较了与患者的股骨髋臼撞击和焦点软骨缺损传统微骨折（MF）技术生物重建。两组队列进行了研究;年龄，性别和腾尼斯级匹配用于使用自体基质诱导软骨形成和骨髓抽吸物组合MF和较新的生物重建技术髋关节镜手术之间的结果比较。手术用的Kaplan-Meier生存分析结果后进行了调查预运算和后运算平均IHOT-12得分高达18个月。 111名患者中，46例患者接受MF和65生物重建髋关节镜包括凸轮/钳骨成形和盂唇修复手术。年龄范围为20-69，平均年龄45岁两组，腾尼斯分级如下：0级：26％和30％，等级1：52％对47％，2级：22％和23％MF和生物重建组，分别。 MF和生物重建之间的平均术后IHOT-12得分差异在1年至少随访（P = 0.01，SD 2.8）显著。允许增强的恢复协议生物重建。该MF组有用于转换为18个月的髋关节置换（故障率32.6％由于任何原因）和生物重建一个67.4％的存活率有18个月的100％存活后期可操作地与没有失败的任何理由。这项研究提供的证据基础与关节保留关节镜手术结合生物重建技术优越于MF的进一步支持，即使在焦点软骨缺损，并同时提供外科医生和患者的OA差距潜在的桥接的脸。

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