首页> 美国卫生研究院文献>Morbidity and Mortality Weekly Report >Laboratory Modeling of SARS-CoV-2 Exposure Reduction Through Physically Distanced Seating in Aircraft Cabins Using Bacteriophage Aerosol — November 2020
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Laboratory Modeling of SARS-CoV-2 Exposure Reduction Through Physically Distanced Seating in Aircraft Cabins Using Bacteriophage Aerosol — November 2020

机译:使用噬菌体气雾剂在飞机舱内物理距离座位降低SARS-COV-2暴露的实验室建模 - 11月20日

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摘要

Aircraft can hold large numbers of persons in close proximity for long periods, which can increase the risk for transmission of infectious disease.* Current CDC guidelines recommend against travel for persons who have not been vaccinated against COVID-19, and a January 2021 CDC order requires masking for all persons while on airplanes.†,§ Research suggests that seating proximity on aircraft is associated with increased risk for infection with SARS-CoV-2, the virus that causes COVID-19 (1,2). However, studies quantifying the benefit of specific distancing strategies to prevent transmission, such as keeping aircraft cabin middle seats vacant, are limited. Using bacteriophage MS2 virus as a surrogate for airborne SARS-CoV-2, CDC and Kansas State University (KSU) modeled the relationship between SARS-CoV-2 exposure and aircraft seating proximity, including full occupancy and vacant middle seat occupancy scenarios. Compared with exposures in full occupancy scenarios, relative exposure in vacant middle seat scenarios was reduced by 23% to 57% depending upon the modeling approach. A 23% exposure reduction was observed for a single passenger who was in the same row and two seats away from the SARS-COV-2 source, rather than in an adjacent middle seat. When quantifying exposure reduction to a full 120-passenger cabin rather than to a single person, exposure reductions ranging from 35.0% to 39.4% were predicted. A 57% exposure reduction was observed under the vacant middle seat condition in a scenario involving a three-row section that contained a mix of SARS-CoV-2 sources and other passengers. Based on this laboratory model, a vacant middle seat reduces risk for exposure to SARS-CoV-2 from nearby passengers. These data suggest that increasing physical distance between passengers and lowering passenger density could help reduce potential COVID-19 exposures during air travel. Physical distancing of airplane passengers, including through policies such as middle seat vacancy, could provide additional reductions in SARS-CoV-2 exposure risk.
机译:飞机可以长期抵达大量的人,这可能会增加传染病传播的风险。*目前的CDC指南建议对尚未接种Covid-19疫苗的人和1月2021年1月的CDC订单的旅行。在飞机上需要掩盖所有人。§,§研究表明,飞机座位接近与SARS-COV-2感染的风险增加,导致Covid-19的病毒(1,2)。然而,量化对防止传输的特定远距离策略的益处,例如保持飞机舱中间座位空置的有限。使用噬菌体MS2病毒作为机载SARS-COV-2的代理,CDC和堪萨斯州立大学(KSU)建模了SARS-COV-2曝光和飞机座位之间的关系,包括全部占用和空置的中间座位占用场景。与全部占用场景中的暴露相比,空缺中间座椅情景中的相对暴露根据建模方法减少23%至57%。对于在同一行和远离SARS-COV-2来源的单个乘客,而不是在相邻的中间座椅中观察到23%的乘客。当量化曝光降低到整个120乘客舱而不是一个人,预测从35.0%到39.4%的暴露减少。在涉及包含SARS-COV-2来源和其他乘客的混合的三排部分的场景中观察到57%的曝光减少。基于该实验室模型,空置的中间座椅从附近的乘客那里减少了暴露于SARS-COV-2的风险。这些数据表明,乘客和降低乘客密度之间的物理距离可能有助于减少在空气行程期间减少潜在的Covid-19曝光。飞机乘客的身体偏移,包括通过中间座位空缺等政策,可以在SARS-COV-2暴露风险中提供额外的降低。

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