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Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo-controlled trial

机译：口服母体阴道微生物在出生时恢复患有剖腹产婴儿的肠道微生物组发育：试点随机安慰剂对照试验

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Birth by caesarean section (CS) is associated with aberrant gut microbiome development and greater disease susceptibility later in life. We investigated whether oral administration of maternal vaginal microbiota to infants born by CS could restore their gut microbiome development in a pilot single-blinded, randomised placebo-controlled trial (Australian New Zealand Clinical Trials Registry, ACTRN12618000339257).

机译：通过剖腹产（CS）出生与异常肠道微生物组发育有关，并在生命后面的疾病易感性有关。我们调查了母亲阴道微生物的口服给CS出生的婴儿是否可以在试验单一盲目的随机安慰剂对照试验（澳大利亚新西兰临床试验登记处，ACTRN12618000339257）中恢复他们的肠道微生物组发育。

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期刊名称 EBioMedicine
作者
Brooke C. Wilson; Éadaoin M. Butler; Celia P. Grigg; José G.B. Derraik; Valentina Chiavaroli; Nicholas Walker; Suma Thampi; Christine Creagh; Abigail J. Reynolds; Tommi Vatanen; Justin M. OSullivan; Wayne S. Cutfield;
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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 13
原文格式 PDF
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机译：阴道播种;剖腹产;出生;肠道微生物组;婴儿开发;Metagenomics;母体菌传动;

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1. Re: Maternal outcomes at 3 months after planned caesarean section versus planned vaginal birth for twin pregnancies in the Twin Birth Study: a randomised controlled trial Counselling is difficult when outcomes are associated with mode of delivery and not the plan of mode of delivery Reply [J] . Salvesen K. A. BJOG: an international journal of obstetrics and gynaecology . 2016,第4期

机译：回复：在双胞胎研究中，计划剖腹产后3个月的孕妇结局与双胎妊娠的计划阴道分娩相比：一项随机对照试验当结局与分娩方式相关而不与分娩方式相关时，咨询非常困难
2. Re: Maternal outcomes at 3 months after planned caesarean section versus planned vaginal birth for twin pregnancies in the Twin Birth Study: a randomised controlled trial: Counselling is difficult when outcomes are associated with mode of delivery and not the plan of mode of delivery [J] . Hutton Eileen K., Hannah Mary E., Ross Susan, BJOG: an international journal of obstetrics and gynaecology . 2016,第4期

机译：回复：在双胞胎研究中，计划剖腹产后3个月的孕妇结局与双胎妊娠的计划阴道分娩相比：一项随机对照试验：当结局与分娩方式相关而不与分娩方式相关时，咨询困难
3. Maternal outcomes at 3months after planned caesarean section versus planned vaginal birth for twin pregnancies in the Twin Birth Study: a randomised controlled trial [J] . Hutton E. K., Hannah M. E., Ross S., BJOG: an international journal of obstetrics and gynaecology . 2015,第12期

机译：双胎妊娠研究中，计划剖腹产与计划阴道分娩后3个月的双胎妊娠母亲结局：一项随机对照试验
4. Birth after caesarean study – planned vaginal birth or planned elective repeat caesarean for women at term with a single previous caesarean birth: protocol for a patient preference study and randomised trial [O] . Jodie M Dodd, Caroline A Crowther, Janet E Hiller, 2007

机译：剖腹产后出生–曾有一次剖腹产的足月孕妇计划进行阴道分娩或计划进行选择性剖腹产：患者偏爱研究和随机试验的方案
5. Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo-controlled trial [O] . Brooke C. Wilson, Éadaoin M. Butler, Celia P. Grigg, 2021

机译：口服母体阴道微生物在出生时恢复患有剖腹产婴儿的肠道微生物组发育：试点随机安慰剂对照试验

Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo-controlled trial

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