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Investigation of Flexible Arrayed Lactate Biosensor Based on Copper Doped Zinc Oxide Films Modified by Iron–Platinum Nanoparticles

机译:基于铁 - 铂纳米粒子改性铜掺杂氧化锌膜的柔性排列乳酸生物传感器的研究

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摘要

Potentiometric biosensors based on flexible arrayed silver paste electrode and copper-doped zinc oxide sensing film modified by iron-platinum nanoparticles (FePt NPs) are designed and manufactured to detect lactate in human. The sensing film is made of copper-doped zinc oxide (CZO) by a radio frequency (RF) sputtering system, and then modified by iron-platinum nanoparticles (FePt NPs). The surface morphology of copper-doped zinc oxide (CZO) is analyzed by scanning electron microscope (SEM). FePt NPs are analyzed by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The average sensitivity, response time, and interference effect of the lactate biosensors are analyzed by voltage-time (V-T) measurement system. The electrochemical impedance is analyzed by electrochemical impedance spectroscopy (EIS). The average sensitivity and linearity over the concentration range 0.2–5 mM are 25.32 mV/mM and 0.977 mV/mM, respectively. The response time of the lactate biosensor is 16 s, with excellent selectivity.
机译:设计并制造基于柔性排列的银浆料电极和由铁 - 铂纳米颗粒(FEST NPS)改性的铜掺杂氧化锌感测膜的电位体传感器以检测人中的乳酸。传感膜通过射频(RF)溅射系统由铜掺杂的氧化锌(CZO)制成,然后通过铁铂纳米颗粒(FEST NP)来改性。通过扫描电子显微镜(SEM)分析铜掺杂氧化锌(CZO)的表面形态。通过X射线衍射(XRD)和傅里叶变换红外光谱(FTIR)分析了备用NPS。通过电压 - 时间(V-T)测量系统分析乳酸生物传感器的平均灵敏度,响应时间和干扰效应。通过电化学阻抗光谱(EIS)分析电化学阻抗。浓度范围内的平均灵敏度和线性度分别为25.32mV / mm和0.977 mV / mm。乳酸生物传感器的响应时间为16秒,选择性优异。

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