首页> 美国卫生研究院文献>Journal of Blood Transfusion >High Rates of Hepatitis B and C and HIV Infections among Blood Donors in Cameroon: A Proposed Blood Screening Algorithm for Blood Donors in Resource-Limited Settings
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High Rates of Hepatitis B and C and HIV Infections among Blood Donors in Cameroon: A Proposed Blood Screening Algorithm for Blood Donors in Resource-Limited Settings

机译:喀麦隆献血者中乙型和丙型肝炎和艾滋病毒的高感染率:资源受限地区献血者的建议血液筛查算法

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摘要

Background. Infections with human immunodeficiency virus (HIV), hepatitis B (HBV), and hepatitis C virus (HCV) are currently major public health problems. Methods. A retrospective study was conducted from January to June 2008 at the Blood Bank of the Central Hospital, Yaoundé (Cameroon). The objective was to study the prevalence of HIV, HBV, and HCV and their coinfections among blood donors. Results. A total of 4650 donors were identified, and the sex ratio (male/female) was 14/1. The median age of donors was 28 years (range: 16 to 69 years). Among blood donors, HBV, HIV, and HCV infection prevalences were 12.14%  (n = 565) , 4.44%  (n = 206), and 1.44%  (n = 67), respectively. Coinfection with HIV and HBV was observed among 0.77% donors, followed by hepatitis B and C co-infection (0.21%) and HIV and HCV coinfection (0.06%). Co-infection with HIV-HBV-HCV was encountered in 2 donors. The HIV, HBV, and HCV infections lead to a destruction of one out of six sets of blood collected. Conclusion. There is a need to review policies for blood collection from donors, by modifying the algorithm of blood donors testing. Pretesting potential donors using rapid tests could help to avoid collection and destruction of (infected) blood.
机译:背景。目前,人类免疫缺陷病毒(HIV),乙型肝炎(HBV)和丙型肝炎病毒(HCV)感染是主要的公共卫生问题。方法。回顾性研究于2008年1月至6月在雅温得(喀麦隆)中央医院血库进行。目的是研究献血者中HIV,HBV和HCV的流行及其共感染。结果。总共确定了4650个捐助者,性别比(男性/女性)为14/1。供体的中位年龄为28岁(范围:16至69岁)。在献血者中,HBV,HIV和HCV感染率分别为12.14%(n = 565),4.44%(n = 206)和1.44%(n = 67)。在0.77%的捐献者中,艾滋病毒和HBV合并感染,其次是乙肝和丙肝共同感染(0.21%),以及HIV和HCV合并感染(0.06%)。 2名捐助者遇到了HIV-HBV-HCV的合并感染。 HIV,HBV和HCV感染导致六种血液中的一种被破坏。结论。有必要通过修改献血者测试算法来审查从献血者那里采血的政策。使用快速测试对潜在的捐献者进行预测试可以帮助避免收集和破坏(感染的)血液。

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