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首页> 美国卫生研究院文献>JARO: Journal of the Association for Research in Otolaryngology >Modeling the dependence of the distortion product otoacoustic emission response on primary frequency ratio
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Modeling the dependence of the distortion product otoacoustic emission response on primary frequency ratio

机译：建模失真产物耳声发射响应对初级频率比的依赖性

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摘要

When measured as a function of primary frequency ratio r = f2/f1, using a constant f2, distortion product otoacoustic emission (DPOAE) response demonstrates a bandpass shape, previously interpreted as the evidence for a cochlear “second filter.” In this study, an alternate, interference-based explanation, previously advanced in variants, is forwarded on the basis of experimental data along with numerical and analytical solutions of nonlinear and linear cochlear models. The decrease of the DPOAE response with increasing and decreasing ratios is explained by a diminishing “overlap” generation region and the onset of negative interference among wavelets of different phase, respectively. In this paper, the additional quantitative hypothesis is made that negative interference becomes the dominant effect when the spatial width of the generation (overlap) region exceeds half a wavelength of the DPOAE wavelets. Therefore, r is predicted to be optimal when this condition is matched. Additionally, the minimum on the low-ratio side of the DPOAE curve is predicted to occur as the overlap region width equals one wavelength. As the width of the overlap region depends on both tuning and ratio, while wavelength depends on tuning only, an experimental method for estimating tuning from either the width of the pass band or the optimal ratio of the DPOAE vs. ratio curve has been theoretically formulated and evaluated using numerical simulations. A linear model without the possibility of nonlinear suppression is shown to reasonably approximate data from human subjects at low ratios reinforcing the relevance of the proposed negative interference effect. The different dependence of the distortion and reflection DPOAE components on r as well as the nonmonotonic behavior of the distortion component observed at very low ratios are also in agreement with this interpretation.
机译：当使用常数f2作为初级频率比r = f2 / f1的函数进行测量时，失真产物耳声发射（DPOAE）响应显示出带通形状，以前被解释为耳蜗“第二滤波器”的证据。在这项研究中，基于实验数据以及非线性和线性耳蜗模型的数值和解析解，转发了先前在变量中有所改进的基于干扰的替代解释。 DPOAE响应随比率增大和减小而减小的现象分别由“重叠”生成区域减小和不同相位的小波之间出现负干扰引起。在本文中，另外的定量假设是，当生成（重叠）区域的空间宽度超过DPOAE小波波长的一半时，负干扰将成为主要影响。因此，当该条件匹配时，r被预测为最佳。另外，由于重叠区域的宽度等于一个波长，预计会发生DPOAE曲线的低比率侧的最小值。由于重叠区域的宽度取决于调谐和比率，而波长仅取决于调谐，因此理论上已经制定了一种通过通带宽度或DPOAE相对比率曲线的最佳比率估算调谐的实验方法。并使用数值模拟进行评估。线性模型显示了非线性抑制的可能性，该模型可以合理地近似以较低的比例从人类对象获得的数据，从而增强了所提出的负面干扰效应的相关性。畸变和反射DPOAE分量对r的不同依赖性以及以非常低的比率观察到的畸变分量的非单调性也与该解释一致。

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