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首页> 美国卫生研究院文献>The Journal of the American College of Clinical Wound Specialists >Clinical Effectiveness of Hyperbaric Oxygen Therapy in Complex Wounds
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Clinical Effectiveness of Hyperbaric Oxygen Therapy in Complex Wounds

机译：复杂伤口高压氧治疗的临床效果

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Hyperbaric Oxygen (HBO, HBO2) Therapy is a non-invasive therapy. It has been applied as adjuvant treatment in many medical conditions over the past 50 years. Different treatment protocols have been proven effective for specifically indicated conditions. To evaluate the clinical effectiveness of Hyperbaric Oxygen (HBO) Therapy as an adjunctive treatment for patients with complex wounds. In this prospective cohort study, 40 patients with complex wounds were included. All patients received HBO. HBO was delivered with 100% oxygen for 90 min at 2.0–2.4 ATA. Wound sizes were assessed by one wound surgeon before, during, and every 2 weeks for a total of 12 months after HBO. An analysis of demographic data, wound size and wound photography was performed. Over the 22-month period ending October 31, 2013, 40 patients (21 men and 19 women) with a mean age of 59.73 (range, 29–88) with complex wounds were included. All complex wounds studied were at least 6 months old. The mean wound size was 16.72 cm2 in diameter. Thirty-one patients with complex wounds healed after the completion of a series of HBO treatments (77.5%). Two orocutaneous fistulas were completely closed without further surgery. After 5 HBO treatments, the wound size reduced by 29.7% on average (p = 1.24 × 10−6). After 10 HBO treatments, the wound size statistically significantly reduced by an additional 16.9% (p = 0.0002). There were no complications in this study. Wound healing process was accelerated by HBO. Significant wound size reduction was noted after 5 HBO treatments. Because the biggest reduction in wound size occurred within the first 10 HBO treatments, it is important to conduct these first treatments without interruption. HBO is an effective and safe treatment modality for complex wounds.
机译：高压氧（HBO，HBO2）治疗是一种非侵入性治疗。在过去的50年中，它已在许多医疗条件下用作辅助治疗。事实证明，不同的治疗方案对于特定的疾病有效。为了评估高压氧（HBO）疗法作为复杂伤口患者的辅助治疗的临床效果。在这项前瞻性队列研究中，纳入了40例具有复杂伤口的患者。所有患者均接受HBO治疗。在2.0-2.4 ATA下，HBO用100％的氧气输送了90分钟。在HBO术后12个月之前，期间和每2周，由一名伤口外科医师评估伤口大小。进行了人口统计数据，伤口大小和伤口摄影的分析。在截至2013年10月31日的22个月内，纳入40例平均年龄为59.73（范围为29-88）的复杂伤口患者（21例男性和19例女性）。研究的所有复杂伤口均至少6个月大。平均伤口直径为16.72 cm 2 。完成一系列HBO治疗后，有31例具有复杂伤口的患者ed愈（77.5％）。两个口皮肤瘘完全闭合，无需进一步手术。经过5次HBO治疗后，伤口大小平均减少了29.7％（p = 1.24×10 -6 ）。经过10次HBO治疗后，伤口大小在统计学上显着减少了16.9％（p = 0.0002）。这项研究没有并发症。 HBO加速了伤口愈合过程。在5次HBO治疗后，伤口大小明显减少。由于伤口大小的最大减少发生在前10次HBO治疗中，因此必须不间断地进行这些最初的治疗很重要。 HBO是治疗复杂伤口的有效且安全的方法。

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