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首页> 美国卫生研究院文献>i-Perception >Fabrication of Prototype of Artificial Retina Adapted to a Curved Image Plane Based on Arrayed PMMA Microfibers
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Fabrication of Prototype of Artificial Retina Adapted to a Curved Image Plane Based on Arrayed PMMA Microfibers

机译：基于阵列PMMA超细纤维的适应于弯曲像面的人工视网膜原型制作

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摘要

The traditional visual prosthesis combines both a camera and an electrode array implanted on the visual neural networks. Here, we introduce a new design of artificial retina which integrate the transmission of image and the electrical stimulation of cortical neurons on a single PMMA micro fiber. It is comprised of multiple PMMA microfibers with both ends connected with one flexible and one rigid substrates. The flexible one is a PDMS mold of microrods and ready to conform to a curved image plane. The rigid one is in the form of a silica plate coated with a PMMA thin film and could be attached to a CMOS image sensor for the evaluation of its optical performance. The multiple PMMA microfibers were directly drawn from liquid PMMA thin film with PDMS rods. With arrayed PMMA microfibers, the image planes could be transferred from the flexible to rigid substrate. Each PMMA microfiber delivers a part of the image the PDMS mold transmits. Incorporated with O/E convertors, each micro fiber could function as an unit of electrical stimulation in accordance with part of the image the artificial retina delivered and is ready to function as a cortical neural prosthesis in the future application.
机译：传统的视觉假体将摄像头和植入视觉神经网络的电极阵列结合在一起。在这里，我们介绍了一种人工视网膜的新设计，该技术在单个PMMA超细纤维上整合了图像的传输和皮质神经元的电刺激。它由多根PMMA超细纤维组成，两端均与一个柔性和一个刚性基材相连。柔性的是微棒的PDMS模具，可以顺应弯曲的图像平面。刚性的是涂有PMMA薄膜的二氧化硅板的形式，可以连接到CMOS图像传感器以评估其光学性能。使用PDMS棒从液态PMMA薄膜直接拉出多条PMMA超细纤维。使用排列的PMMA超细纤维，图像平面可以从柔性基板转移到刚性基板。每个PMMA超细纤维都会传递PDMS模具传输的一部分图像。结合O / E转换器，每条微纤维都可以根据人工视网膜所传递的图像的一部分，充当电刺激的单位，并准备在未来的应用中充当皮层神经假体。

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