首页> 美国卫生研究院文献>Internal Medicine >An Autopsy Case of Myeloperoxidase-anti-neutrophil Cytoplasmic Antibody (MPO-ANCA)-associated Vasculitis Accompanied by Cryoglobulinemic Vasculitis Affecting the Kidneys Skin and Gastrointestinal Tract

【2h】

An Autopsy Case of Myeloperoxidase-anti-neutrophil Cytoplasmic Antibody (MPO-ANCA)-associated Vasculitis Accompanied by Cryoglobulinemic Vasculitis Affecting the Kidneys Skin and Gastrointestinal Tract

机译：骨髓过氧化物酶抗中性粒细胞胞质抗体（MPO-ANCA）相关的血管炎伴低温肾小管血管炎的尸检病例影响肾脏皮肤和胃肠道

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and cryoglobulinemic vasculitis (CV) rarely coexist. An 83-year-old woman was admitted with rapidly progressive renal failure, gastrointestinal hemorrhage and purpura with myeloperoxidase (MPO)-ANCA positivity and cryoglobulinemia. Despite intensive immunosuppressive treatment, she died of aspergillus pneumonia. Autopsy revealed necrotizing crescentic glomerulitis in the majority of the glomeruli, accompanied by partially membranoproliferative-like glomerular changes. Immunofluorescence staining revealed the presence of neutrophil extracellular trap (NET) formation in the glomeruli and cutaneous arteries. These pathological findings suggested that MPO-AAV and/or CV caused NET formation, leading to lethal systemic vasculitis.

机译：抗中性粒细胞胞浆抗体（ANCA）相关血管炎（AAV）和冰球蛋白血症性血管炎（CV）很少并存。一名83岁的女性因髓过氧化物酶（MPO）-ANCA阳性和冷球蛋白血症而迅速进展为肾功能衰竭，胃肠道出血和紫癜。尽管进行了严格的免疫抑制治疗，她仍死于曲霉性肺炎。尸检显示大部分肾小球坏死性新月型肾小球炎，伴有部分膜增生性肾小球改变。免疫荧光染色显示在肾小球和皮肤动脉中存在中性粒细胞胞外陷阱（NET）。这些病理结果表明，MPO-AAV和/或CV引起NET的形成，导致致命的系统性血管炎。

著录项

期刊名称 Internal Medicine
作者
Jumpei Hasegawa; Sachiko Wakai; Momoko Kono; Yusuke Imaizumi; Sakiko Masuda; Akihiro Ishizu; Kazuho Honda;
展开▼
作者单位

展开▼
年(卷),期 2018(57),18
年度 2018
页码 2739–2745
总页数 7
原文格式 PDF
正文语种
中图分类基础医学;
关键词
ANCA anti-neutrophil cytoplasmic antibody cryoglobulin vasculitis neutrophil extracellular traps NETs;

机译：ANCA;抗中性粒细胞胞浆抗体;冰球蛋白;血管炎;中性粒细胞胞外捕获物;NETs;

相似文献

外文文献
中文文献
专利

1. An Autopsy Case of Myeloperoxidase-anti-neutrophil Cytoplasmic Antibody (MPO-ANCA)-associated Vasculitis Accompanied by Cryoglobulinemic Vasculitis Affecting the Kidneys, Skin, and Gastrointestinal Tract [J] . Jumpei Hasegawa, Sachiko Wakai, Momoko Kono, Internal medicine. . 2018,第18期

机译：骨髓过氧化物酶抗中性粒细胞胞质抗体（MPO-ANCA）相关的血管炎伴有肾，皮肤和胃肠道的低温血色素血管炎的尸检病例。
2. From Kidney to Brain: An Uncommon Severe Relapse of Myeloperoxidase Anti-Neutrophil Cytoplasmic Antibody (MPO-ANCA) Vasculitis [J] . Tiago Araújo, Rúben Maia, Jo?o Massano, Cureus. . 2021,第3期

机译：从肾脏到脑中：肌释放酶抗嗜中性粒细胞细胞质抗体（MPO-ANCA）血管炎的罕见严重复发
3. Systematic review of the role of rituximab in treatment of antineutrophil cytoplasmic autoantibody-associated vasculitis, hepatitis C virus-related cryoglobulinemic vasculitis, Henoch–Sch?nlein purpura, ankylosing spondylitis, and Raynaud's phenomenon [J] . Rbab Taha, Hadeel El-Haddad, Abdulqader Almuallim, Open access Rheumatology: Research and Reviews . 2017,第4期

机译：系统评价利妥昔单抗在抗中性粒细胞胞浆自身抗体相关血管炎，丙型肝炎病毒相关低温球囊性血管炎，Henoch–Sch？nlein紫癜，强直性脊柱炎和雷诺现象中的作用
4. The antioxidant potentials of enzymatically hydrolyzed canned red kidney beans (Phaseolus vulgaris L.) in the in vitro simulated gastrointestinal tract [C] . American Society of Agricultural and Biological Engineers Annual International Meeting . 2019

机译：在体外模拟胃肠道中酶促水解红芸豆（Photholusulus L.）的抗氧化潜力
5. Systematic review of the role of rituximab in treatment of antineutrophil cytoplasmic autoantibody-associated vasculitis hepatitis C virus-related cryoglobulinemic vasculitis Henoch–Schönlein purpura ankylosing spondylitis and Raynaud’s phenomenon [O] . Rbab Taha, Hadeel El-Haddad, Abdulqader Almuallim, 2017

机译：系统评价利妥昔单抗在抗中性粒细胞胞浆自身抗体相关血管炎丙型肝炎病毒相关低温球蛋白血管炎Henoch-Schönlein紫癜强直性脊柱炎和雷诺现象中的作用
6. Henoch-Schoenlein purpura accompanied with myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) associated vasculitis with elevated serum interleukin-10. [O] . Hiroshi Ishida 2005

机译：Henoch-schoenlein purpura伴有Myeloceroxidase-antiNeutrophil细胞质抗体（MPO-ANCA）相关的血管炎，血清白细胞介素-10升高。

An Autopsy Case of Myeloperoxidase-anti-neutrophil Cytoplasmic Antibody (MPO-ANCA)-associated Vasculitis Accompanied by Cryoglobulinemic Vasculitis Affecting the Kidneys Skin and Gastrointestinal Tract

摘要

著录项

相似文献

相关主题

期刊订阅