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首页> 美国卫生研究院文献>International Medical Case Reports Journal >Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma
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Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma

机译：全身性恶性黑色素瘤的典型特征是负电视网膜电图和夜视

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摘要

We report a unique case of a female who presented with unilateral disk edema, melanoma-associated retinopathy symptoms, and suggestive electroretinography findings preceding a diagnosis of metastatic melanoma of the pelvis. A 63-year-old female presented with complaints of seeing shimmering lights and nyctalopia, and underwent an extensive ophthalmological and electrophysiological examination. Best-corrected visual acuity was 20/20 in both eyes. Visual fields showed relative central scotomata and concentric narrowing. Slit-lamp and fundus examinations were normal. Rod-specific electroretinography responses were severely reduced, with electronegative maximal combined rod–cone responses and delayed cone responses with normal amplitude. Melanoma-associated retinopathy was suspected. Extensive systemic and internal evaluation revealed occult metastatic melanoma of the pelvis of unknown primary site.
机译：我们报告了一个女性的独特病例，该女性呈现出单侧椎间盘水肿，黑色素瘤相关的视网膜病变症状，以及在诊断为骨盆转移性黑色素瘤之前提示的视网膜电图检查结果。一名63岁的女性因抱怨看到微弱的灯光和夜视而接受了广泛的眼科和电生理检查。两只眼睛的最佳矫正视力为20/20。视野显示相对中央盲孔和同心变窄。裂隙灯和眼底检查正常。棒特异的视网膜电图显着降低，负电最大组合的棒锥反应和延迟的锥体反应具有正常幅度。怀疑与黑色素瘤相关的视网膜病变。广泛的系统和内部评估发现未知原发部位的骨盆隐匿性转移性黑色素瘤。

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