首页> 美国卫生研究院文献>International Journal of Pediatrics Adolescent Medicine >A randomized study on a 3-month versus a 7-month prednisolone regimen for the initial episode of childhood idiopathic nephrotic syndrome at a large Saudi center
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A randomized study on a 3-month versus a 7-month prednisolone regimen for the initial episode of childhood idiopathic nephrotic syndrome at a large Saudi center

机译:在沙特大型中心进行的3个月和7个月泼尼松龙方案治疗儿童特发性肾病综合征初始发作的随机研究

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摘要

Background and objectivesThe standard International Study of Kidney Disease in Children (ISKDC) regimen of prednisolone of 2 months duration for the treatment of the initial episode of Idiopathic Nephrotic Syndrome (INS) was associated with a high relapse rate. The long prednisolone protocols were introduced in order to reduce the relapse rate and steroid toxicities. The main objective of this study was to assess the efficacy and safety of a 3 months protocol of prednisolone versus a 7 months protocol for the first episode of idiopathic nephrotic syndrome.
机译:背景与目的标准的泼尼松龙治疗儿童早期国际肾脏病研究(ISKDC)疗程为2个月,用于治疗特发性肾病综合症(INS)的初始发作,且复发率高。引入了长期泼尼松龙方案以降低复发率和类固醇毒性。这项研究的主要目的是评估泼尼松龙3个月方案与首发特发性肾病综合征7个月方案的疗效和安全性。

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