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首页> 美国卫生研究院文献>International Journal of Nanomedicine >Influence of needle-like morphology on the bioactivity of nanocrystalline wollastonite – an in vitro study
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Influence of needle-like morphology on the bioactivity of nanocrystalline wollastonite – an in vitro study

机译：针状形态对纳米晶硅灰石生物活性的影响–体外研究

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摘要

In the past 2 decades, wollastonite has been studied thoroughly for its application as a bone implant material due to its biocompatibility, high mechanical strength, and excellent bioactivity when compared to calcium phosphates bioceramics. Wollastonite was prepared through the low-temperature sol-gel combustion method using urea as the fuel, nitrate ions and nitric acid as the oxidizer. Calcium nitrate and tetraethyl orthosilicate were taken as the source of calcium and silica. The synthesized wollastonite were characterized by Fourier transform infrared spectroscopy for the identification of characteristic functional group and powder X-ray diffraction for the phase identification. Employing urea as a fuel resulted in needle-like morphology of the particles, which was confirmed by scanning electron microscopy and transmission electron microscopy. It was observed that the needle-like morphology enhances the mechanical properties such as elasticity and compressive strength and also increases the surface area of the material, which could help in a rapid deposition of hydroxyapatite layer. These properties of wollastonite warrant its application as a new artificial bone material in the field of hard tissue engineering.
机译：在过去的20年中，硅灰石由于具有生物相容性，高机械强度和与磷酸钙生物陶瓷相比优异的生物活性，因此已对其作为骨植入材料的应用进行了深入研究。硅灰石是通过低温溶胶-凝胶燃烧法，以尿素为燃料，硝酸根离子和硝酸为氧化剂制备的。硝酸钙和原硅酸四乙酯作为钙和二氧化硅的来源。通过傅立叶变换红外光谱对合成的硅灰石进行表征，以鉴定特征官能团，并通过粉末X射线衍射进行相鉴定。使用尿素作为燃料导致颗粒的针状形态，这通过扫描电子显微镜和透射电子显微镜得到证实。观察到，针状形态增强了机械性能，例如弹性和抗压强度，并且还增加了材料的表面积，这可以有助于羟基磷灰石层的快速沉积。硅灰石的这些特性保证了其在硬组织工程领域中作为新型人造骨材料的应用。

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