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Oral absorption and lymphatic transport of baicalein following drug–phospholipid complex incorporation in self-microemulsifying drug delivery systems

机译：黄ical素在自微乳化药物递送系统中掺入药物-磷脂复合物后的口服吸收和淋巴运输

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摘要

PurposeThe aims of this study were to prepare a baicalein self-microemulsion with baicalein-phospholipid complex as the intermediate (BAPC-SMEDDS) and to compare its effects with those of conventional baicalein self-microemulsion (CBA-SMEDDS) on baicalein oral absorption and lymphatic transport.

机译：目的本研究的目的是制备以黄ical素-磷脂复合物为中间体（BAPC-SMEDDS）的黄ical素自微乳剂，并将其与常规黄e素自微乳剂（CBA-SMEDDS）对黄ical素口服吸收和淋巴管吸收的作用进行比较。运输。

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期刊名称 International Journal of Nanomedicine
作者
Hengfeng Liao; Yue Gao; Chunfang Lian; Yun Zhang; Bangyuan Wang; Yanfang Yang; Jun Ye; Yu Feng; Yuling Liu;
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作者单位

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年(卷),期 2019(14),-1
年度 2019
页码 7291–7306
总页数 16
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
SMEDDS phospholipid complex baicalein oral bioavailability lymphatic transport;

机译：SMEDDS;磷脂复合物;黄ical素;口服生物利用度;淋巴运输;

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专利

1. Oral absorption and lymphatic transport of baicalein following drug–phospholipid complex incorporation in self-microemulsifying drug delivery systems [J] . Hengfeng Liao, Yue Gao, Chunfang Lian, International Journal of Nanomedicine . 2019,第2期

机译：黄ical素的口服吸收和淋巴运输在药物-磷脂复合物掺入自微乳化给药系统后
2. Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: linear correlation with oral bioavailabilities in rats. [J] . Sun M, Zhai X, Xue K, European journal of pharmaceutical sciences . 2011,第3期

机译：西罗莫司从自微乳化药物递送系统的肠道吸收和肠道淋巴运输，使用单次肠道灌注（SPIP）技术和乳糜微粒流阻滞方法进行评估：与大鼠口服生物利用度呈线性相关。
3. Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides. [J] . Holm R, Porter CJ, Edwards GA, European journal of pharmaceutical sciences . 2003,第1期

机译：在含有结构化甘油三酸酯的自微乳化药物递送系统（SMEDDS）中给药后，在三插管犬模型中检查氟番嘌呤的口服吸收和淋巴运输。
4. Development of Self-Microemulsifying Drug Delivery Systems (SMEDDS) for Oral Bioavailability Enhancement of Saquinavir [C] . Deepa Patel Controlled Release Society Annual Meeting and Exposition . 2007

机译：开发自微乳化药物递送系统（SMEDDS），以提高沙奎那韦的口服生物利用度
5. Development and characterization of a solid self-microemulsifying drug delivery system (SMEDDS) of albendazole and evaluation of oral bioavailability in rabbits. [D] . Mukherjee, Tusharmouli. 2010

机译：阿苯达唑固体自微乳化药物递送系统（SMEDDS）的开发和表征以及兔口服生物利用度的评估。
6. Enhanced intestinal lymphatic absorption of saquinavir through supersaturated self-microemulsifying drug delivery systems [O] . Kanghee Jo, Hyeongmin Kim, Prakash Khadka, 2020

机译：通过超饱和自微乳化药物递送系统增强沙奎那韦在肠道的淋巴吸收
7. Development and Evaluation of Docetaxel-Phospholipid Complex Loaded Self-Microemulsifying Drug Delivery System: Optimization and In Vitro/Ex Vivo Studies [O] . Miao Wang, Sung-Kyun You, Hong-Ki Lee, 2020

机译：多西紫杉醇 - 磷脂复合载自乳化药物递送系统的开发和评价：优化和体外/ exVivo研究

Oral absorption and lymphatic transport of baicalein following drug–phospholipid complex incorporation in self-microemulsifying drug delivery systems

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