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首页> 美国卫生研究院文献>International Journal of Molecular Sciences >Flavonoid Analyses and Antimicrobial Activity of Various Parts of Phaleria macrocarpa (Scheff.) Boerl Fruit
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Flavonoid Analyses and Antimicrobial Activity of Various Parts of Phaleria macrocarpa (Scheff.) Boerl Fruit

机译：东方鸡蛋花果实各部位的类黄酮分析及抑菌活性

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摘要

Phaleria macrocarpa (Scheff.) Boerl (Thymelaceae) is commonly known as ‘Crown of God’, ‘Mahkota Dewa’, and ‘Pau’. It originates from Papua Island, Indonesia and it grows in tropical areas. Empirically, it is potent in treating the hypertensive, diabetic, cancer and diuretic patients. It has a long history of ethnopharmacological usage, and the lack of information about its biological activities led us to investigate the possible biological activities by characterisation of flavonoids and antimicrobial activity of various part of P. macrocarpa against pathogenic bacteria and fungi. The results showed that kaempferol, myricetin, naringin, and rutin were the major flavonoids present in the pericarp while naringin and quercetin were found in the mesocarp and seed. Furthermore, the antibacterial activity of different parts of P. macrocarpa fruit showed a weak ability to moderate antibacterial activity against pathogenic tested bacteria (inhibition range: 0.93–2.17 cm) at concentration of 0.3 mg/disc. The anti fungi activity was only found in seed extract against Aspergillus niger (1.87 cm) at concentration of 0.3 mg/well. From the results obtained, P. macrocarpa fruit could be considered as a natural antimicrobial source due to the presence of flavonoid compounds.
机译：鹰嘴豆（Scheff。）鲍尔（Thymelaceae）通常被称为“上帝的王冠”，“ Mahkota Dewa”和“ Pau”。它起源于印度尼西亚的巴布亚岛，生长在热带地区。从经验上讲，它对治疗高血压，糖尿病，癌症和利尿患者有效。它具有人类药理学的悠久历史，缺乏有关其生物活性的信息，这使我们通过表征黄酮和大果李子不同部位对病原细菌和真菌的抗菌活性来研究可能的生物活性。结果表明，山茱fer醇，杨梅素，柚皮苷和芦丁是果皮中主要的黄酮类化合物，而柚皮和槲皮素则在中果皮和种子中存在。此外，在浓度为0.3 mg / disc的情况下，山茱P果实不同部位的抗菌活性均显示出弱化对病原测试细菌的抑菌活性（抑制范围：0.93-2.17 cm）。仅在浓度为0.3 mg /孔的黑曲霉（1.87 cm）的种子提取物中发现了抗真菌活性。从获得的结果来看，由于黄酮类化合物的存在，大果果被认为是天然的抗菌源。

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