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首页> 美国卫生研究院文献>International Journal of Endocrinology >Serum Bisphenol A Level in Boys with Cryptorchidism: A Step to Male Infertility?
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Serum Bisphenol A Level in Boys with Cryptorchidism: A Step to Male Infertility?

机译：隐睾症男孩的血清双酚A水平：男性不育的一步吗？

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摘要

Cryptorchidism is the most common congenital birth defect in boys and affects about 2–4% full-term male neonates. Its etiology is multifactorial. Purpose. To evaluate the serum bisphenol A (BPA) levels in boys with cryptorchidism and healthy boys and to assess the risk of environmental exposure to BPA using the authors' questionnaire. The data were acquired from a study on boys with cryptorchidism (n = 98) and a control group (n = 57). Prior to surgery, all patients had BPA serum levels evaluated. The size, position, rigidity of the testis, and abnormality of the epididymis of the undescended testis were assessed. Parents also completed a questionnaire on the risks of exposure to BPA in everyday life. Results. The testes in both groups were similar in size. The turgor of the undescended testis in the group of boys with cryptorchidism was decreased. Free serum BPA level in cryptorchid boys and in the control group was not statistically significant (p > 0.05). The conjugated serum BPA level in cryptorchid boys and in the control group was statistically significant (p ≤ 0.05). Total serum BPA level in cryptorchid boys and in the control group was statistically significant (p < 0.05). Serum total BPA level was related with a positive answer about problems with conception (p < 0.02). Conclusion. Our study indicated that high serum BPA was associated with cryptorchidism.
机译：隐睾症是男孩中最常见的先天性先天性缺陷，影响约2-4％的足月男婴。其病因是多因素的。目的。为了评估隐睾症男孩和健康男孩的血清双酚A（BPA）水平，并使用作者的问卷调查评估环境中双酚A暴露的风险。数据来自一项关于隐睾症男孩（n = 98）和对照组（n = 57）的研究。手术前，所有患者均接受了BPA血清水平评估。评估睾丸的大小，位置，硬度以及未降附睾的附睾异常。父母们还完成了一份关于日常生活中接触双酚A的风险的调查表。结果。两组的睾丸大小相似。隐睾症男孩中睾丸未降的程度降低了。隐睾男孩和对照组的游离血清BPA水平无统计学意义（p> 0.05）。隐睾男孩和对照组的共轭血清BPA水平具有统计学意义（p≤0.05）。隐睾男孩和对照组的总血清BPA水平具有统计学意义（p <0.05）。血清总BPA水平与受孕问题的肯定答案有关（p <0.02）。结论。我们的研究表明，高血清BPA与隐睾症有关。

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