Randomized double-blind placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD

机译：一项随机双盲安慰剂对照试验评估三剂共同悬浮给药技术格隆铵MDI对日本中度至重度COPD患者的疗效和安全性

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摘要

PurposeDue to the burden of COPD in Japan, new pharmacologic treatments are needed to meet patient requirements. This study assessed the efficacy and safety of glycopyrronium (GP) delivered via metered dose inhaler (MDI) in Japanese patients with moderate-to-severe COPD.

机译：目的由于日本的COPD负担，需要新的药物治疗方法以满足患者的需求。这项研究评估了通过计量吸入器（MDI）输送的格隆铵（GP）在日本中重度COPD患者中的疗效和安全性。

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期刊名称 International Journal of Chronic Obstructive Pulmonary Disease
作者
Yasushi Fukushima; Yuji Nakatani; Yumiko Ide; Hisakuni Sekino; Earl St Rose; Shahid Siddiqui; Andrea Maes; Colin Reisner;
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作者单位

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年(卷),期 2018(13),-1
年度 2018
页码 1187–1194
总页数 8
原文格式 PDF
正文语种
中图分类呼吸生理学;
关键词
bronchodilator agents dose–response relationship forced expiratory volume metered dose inhalers COPD;

机译：支气管扩张药;剂量反应关系;强制呼气量;定量吸入器;COPD;

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1. Randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD [J] . Yasushi Fukushima, Yuji Nakatani, Yumiko Ide, International Journal of Chronic Obstructive Pulmonary Disease . 2018,第1期

机译：一项随机，双盲，安慰剂对照试验，评估三剂共同悬浮给药技术格隆铵MDI对日本中度至重度COPD患者的疗效和安全性
2. EFFICACY AND SAFETY OF GLYCOPYRRONIUM/FORMOTEROL FUMARATE DIHYDRATE METERED DOSE INHALER (GFF MDI) DELIVERED USING CO-SUSPENSION DELIVERY TECHNOLOGY IN CHINESE PATIENTS WITH COPD [J] . Zhong Nanshan, Chen Rongchang, Wang Hao-Yan, Respirology : . 2018,第Suppla2期

机译：使用COPD患者的共悬浮递送技术递送糖酮/ Formoterol富马酸富马酸富马酸莫磺酸莫酸酯的疗效和安全性（GFF MDI）
3. Efficacy, safety, and dose response of glycopyrronium administered by metered dose inhaler using co-suspension delivery technology in subjects with intermittent or mild-to-moderate persistent asthma: A randomized controlled trial [J] . Kerwin Edward, Wachtel Andrew, Sher Lawrence, Respiratory medicine . 2018,第期

机译：通过计量剂量吸入器在受试者中使用共悬浮递送技术给药的疗效，安全性和剂量反应，其具有间歇或轻度至中度持续哮喘：随机对照试验
4. A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL TO INVESTIGATE THE EFFICACY OF TIAMULIN IN THE CONTROL OF PORCINE PROLIFERATIVE ENTEROPATHY (PPE) AND PORCINE COLONIC SPIROCHAETOSIS (PCS) UNDER FIELD CONDITIONS [C] . J. Haugegaard, K. Moller, T.K. Jensen, Congress of the International Pig Veterinary Society . 2000

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5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension™ Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD [O] . Leonardo M. Fabbri, Edward M. Kerwin, Selwyn Spangenthal, 2016

机译：中重度COPD患者使用新型Co-Suspension™输送技术计量吸入器（MDI）对吸入的格隆溴铵的剂量反应
7. EFFICACY AND SAFETY OF GLYCOPYRRONIUM/FORMOTEROL FUMARATE DIHYDRATE METERED DOSE INHALER (GFF MDI) DELIVERED USING CO-SUSPENSION DELIVERY TECHNOLOGY IN CHINESE PATIENTS WITH COPD [O] . 2018

机译：使用COPD患者的共悬浮递送技术递送糖酮/ Formoterol Mumarate二水合物计量剂量吸入器（GFF MDI）的疗效和安全性

Randomized double-blind placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD

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