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Image processing and Quality Control for the first 10000 brain imaging datasets from UK Biobank

机译:UK Biobank的前10000个大脑成像数据集的图像处理和质量控制

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摘要

UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline.
机译:UK Biobank是一项大规模的前瞻性流行病学研究,所有数据可供全球研究人员使用。目前,它正在为大脑,心脏和身体MRI,颈动脉超声和低剂量骨骼/脂肪X射线带来100,000名原始参与者。脑成像组件包括6种模式(T1,T2 FLAIR,磁化加权MRI,静息功能磁共振成像,任务功能磁共振成像和扩散磁共振成像)。最近发布了前10,000个成像对象的原始数据和处理后的数据,供一般研究使用。为了帮助将这些数据转换为有用的摘要信息,我们开发了一个自动处理和QC(质量控制)管道,可供其他研究人员使用。在本文中,我们将对UK Biobank脑成像和采集协议进行简要概述,然后详细描述该管线。我们还描述了作为成像协议和处理管线开发的一部分而进行的一些定量研究。

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