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A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report

机译：一项欧洲随机对照试验在标准的长春新碱和卡铂诱导中添加依托泊苷作为儿童（≤16岁）低度神经胶质瘤的18个月治疗方案的一部分–最终报告

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BackgroundThe use of chemotherapy to manage newly diagnosed low grade glioma (LGG) was first introduced in the 1980s. One randomised trial has studied two- versus four-drug regimens with a duration of 12 months of treatment after resection.

机译：背景技术1980年代首次引入了使用化学疗法治疗新诊断的低度神经胶质瘤（LGG）。一项随机试验研究了两种药物与四种药物的治疗方案，在切除后的治疗时间为12个月。

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期刊名称 Elsevier Sponsored Documents
作者
Astrid K. Gnekow; David A. Walker; Daniela Kandels; Susan Picton; Giorgio Perilongo; Jacques Grill; Tore Stokland; Per Eric Sandstrom; Monika Warmuth-Metz; Torsten Pietsch; Felice Giangaspero; René Schmidt; Andreas Faldum; Denise Kilmartin; Angela De Paoli; Gian Luca De Salvo; Astrid K. Gnekow; Irene Slavc; Giorgio Perilongo; Sue Picton; David Walker; Tore Stokland; Per Erik Sandstrom; Niels Clausen; Mikko Arola; Olafur Gisli Jonsson; Ofelia Cruz; Aurora Navajas; Anna Teijeiro; Jacques Grill; Chantal Kalifa; Marie-Anne Raquin; Joris Verlooy; Volkmar Hans; Torsten Pietsch; Wolfram Scheurlen; Johannes Hainfellner; Felice Giangaspero; James Ironside; Keith Robson; Kari Skullerud; David Scheie; NN; Marie-Madeleine Ruchoux; Anne Jouvet; Dominique Figarella-Branger; Arielle Lellouch-Toubiana; Monika Warmuth-Metz; Daniela Prayer; Milena Calderone; Tim Jaspan; Soren Jacob Bakke; Eli Vazquez; Dominique Couanet; Rolf D. Kortmann; Karin Diekmann; Giovanni Scarzello; Roger Taylor; Knut Lote; Jordi Giralt; Christian Carrie; Jean Louis Habrand; Niels Soerensen; Thomas Czech; Paul Chumas; Bengt Gustavson; Michel Zerah; Bettina Wabbels; Maria Luisa Pinello; Alistair Fielder; Ian Simmons; Terje Christoffersen; Gabriele Calaminus; Knut Brockmann; Ronald Straeter; Friedrich Ebinger; Pablo Hernaiz-Driever; Herwig Lackner; Colin Kennedy; Adam Glaser; Bo Stromberg; Jose Ma Indiano; Chantal Rodary; Eric Bouffet; Didier Frappaz; Andreas Faldum; Angela Emser; Gian Luca De Salvo; Suzanne Stephens; David Machin; Marie-Cécile Le Deley; Thore Egeland; Carolyn Freemann; Martin Schrappe; Richard Sposto;
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年(卷),期 -1(81),-1
年度 -1
页码 206–225
总页数 20
原文格式 PDF
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关键词
Low grade glioma Childhood Chemotherapy Randomised trial;

机译：低度神经胶质瘤;儿童期;化疗;随机试验;

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1. A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (= 16 years) low grade glioma - A final report (vol 81, pg 206, 2017) [J] . Gnekow Astrid K., Walker David A., Kandels Daniela, European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2018,第期

机译：欧洲随机对照试验，将依托泊苷添加到标准的长春新碱和卡铂诱导，作为儿童（＆ = 16岁）的18个月治疗方案的一部分（＆ = 16岁）低级胶质瘤 - 最终报告（第81卷，PG 206,2017）
2. A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (<= 16 years) low grade glioma - A final report [J] . Gnekow Astrid K., Walker David A., Kandels Daniela, European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2017,第期

机译：作为儿童（<= 16岁）低级胶质瘤的18个月治疗方案的一部分，欧洲随机对照试验添加依托钠和卡铂诱导的18个月治疗计划的一部分 - 最终报告
3. Long-term outcomes with intensive induction chemotherapy (carboplatin, bleomycin, vincristine and cisplatin/bleomycin, etoposide and cisplatin) and standard bleomycin, etoposide and cisplatin in poor prognosis germ cell tumours: A randomised phase II trial (ISRCTN53643604) [J] . Cafferty Fay H., White Jeff D., Shamash Jonathan, European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2020,第期

机译：具有强化诱导化疗的长期成果（卡铂，博尔霉素，长霉素和顺铂，依托磷脂和顺铂）和标准博来霉素，依托磷脂在预后差异细胞肿瘤中的标准博霉素：随机期II试验（ISRCTN53643604）
4. Prescribed computer games in addition to occlusion versus standard occlusion treatment for childhood amblyopia: a pilot randomised controlled trial [O] . Vijay K. Tailor, Selina Glaze, Payal Khandelwal, 2015

机译：除儿童闭塞与标准儿童闭塞治疗外的处方计算机游戏：儿童随机对照试验
5. A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (<= 16 years) low grade glioma - A final report [O] . Gnekow, Astrid K., Walker, David A., Kandels, Daniela, 2017

机译：欧洲一项随机对照试验，在标准的长春新碱和卡铂诱导中添加依托泊苷，作为儿童（<= 16岁）低度胶质瘤的18个月治疗方案的一部分-最终报告

A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report

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